REENA SINGH

About

I am a Developmental and Stem cell biologist. The focus of my research is cardiovascular diseases and type 1 diabetes. My expertise with mouse developmental genetics, transcriptional regulation, transgenesis, expression profiling and differential gene regulation has enabled me to identify indispensable role of genetic regulators and signaling pathways involved in cardiac development and regeneration. My current area of research is to develop cell replacement therapy for people living with Type 1 diabetes. I am working towards understanding the effect of beta cell niche on its structure and function and modifying the microenvironment to augment stem cell derived-beta cell function.

Employment

• Institute for Stem Cell Biology and Regenerative Medicine Faculty - Reader / Assistant Professor
  2023 - Present
• The University of Sydney School of Medical Sciences Research Focussed Academic - Affiliate
  2022 - 2023
• The University of Sydney School of Medical Sciences Research Focussed Academic - (Lecturer Level B)
  2022 - 2022
• The University of Sydney Postdoctoral Fellow
  2017 - 2021
• Victor Chang Cardiac Research Institute PostDoctoral Scientist
  2011 - 2017
• Medizinische Hochschule Hannover PostDoctoral Scientist
  2009 - 2010

Education

• Medizinische Hochschule Hannover Ph.D.
  2005 - 2009

Projects & Funding

Projects & funding information is unavailable.

Publications (12)

• Enhanced structure and function of human pluripotent stem cell‐derived beta‐cells cultured on extracellular matrix
  STEM CELLS Translational Medicine 2021 DOI: 10.1002/sctm.20-0224
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• Enhanced Structure and Function of Stem Cell-Derived Beta-Like Cells Cultured on Extracellular Matrix
  SSRN Electronic Journal 2020 DOI: 10.2139/ssrn.3525552
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• Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta.
  ELife 2017 DOI: 10.7554/eLife.20994.
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• Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly
  eLife 2017 DOI: 10.7554/eLife.21172
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• PDGF signaling directs cardiomyocyte movement toward the midline during heart tube assembly
  2016 DOI: 10.1101/076703
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• A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels.
  Differentiation 2016 DOI: 10.1016/j.diff.2015.12.003
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• Cardiomyocytes Replicate and their Numbers Increase in Young Hearts.
  Cell 2015 DOI: 10.1016/j.cell.2015.10.038
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• Transgenic rice lines constitutively co-expressing tlp-D34 and chi11 display enhancement of sheath blight resistance
  Biologia plantarum 2013 DOI: 10.1007/s10535-012-0291-z
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• Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation
  Cell Molecular Life Sciences 2012 DOI: 10.1007/s00018-011-0884-2
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• Tbx20, Smads and the Atrioventricular canal.
  Trends in Cardiovascular Medicine 2010 DOI: 10.1016/j.tcm.2010.09.004
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