Employment
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University Leipzig Medical School Director2020 - Present
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Vanderbilt University Professor2005 - Present
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (317)
- Rapid and energy-efficient ultra-large library screening for drug discovery on a SpiNNaker2 neuromorphic chip Save
- Structure-guided compound prioritization strategy for virtual screening identifies putative binders for the nuclear receptor LRH-1 Save
- Architecture of the Gβγ-prefusion SNARE complex reveals the molecular mechanism of inhibition of vesicle fusion Save
- FrustraMPNN: An ultra-fast deep learning tool for proteome-scale analysis of deep mutational single-residue local energetic frustration in proteins Save
- The pathway-independent positive allosteric modulator C1 allows for the identification of active Y4 receptor relevant positions Save
- Superwater as a generative AI framework to predict water molecule positions on protein structures Save
- Data from Acquired Secondary HER2 Mutations Enhance HER2/MAPK Signaling and Promote Resistance to HER2 Kinase Inhibition in Breast Cancer Save
- Supplementary Data from Acquired Secondary HER2 Mutations Enhance HER2/MAPK Signaling and Promote Resistance to HER2 Kinase Inhibition in Breast Cancer Save
- General Trends in the Calnexin-Dependent Expression and Pharmacological Rescue of Clinical CFTR Variants Save
- General Trends in the Calnexin-Dependent Expression and Pharmacological Rescue of Clinical CFTR Variants Save