0000-0001-8973-5529 About
Research Experience and Research Interest: Involved in the field of Mammalian Reproductive Physiology and proposed a molecular mechanism for sperm storage which is one of the unique aspects of bat reproduction. We are first to demonstrate the role of androgen in prolonged sperm storage in the female genital tract of S. heathi and showed androgen via non-genomic MAPK signaling pathway stimulate Bcl2 (anti apoptotic) in utero-tubal junction. These new findings on sperm storage may help in understanding of the mechanisms behind adaptive sperm storage. It may also generate practical outcomes such as the ability to develop successful long-term, but non-cryogenic, sperm storage methods for use in reproductive technologies.
We also demonstrated the adiposity associated impairment of testicular physiology in bat. Risk of obesity is alarming in recent days. This study will add new information on adiposity associated impairment to male fertility. At present we are involved in the regulation of testicular physiology under different conditions such as heat stress, diabetes and environmental toxicant and trying to find out possible improvement of these conditions by phytochemicals. Also involve in metabolic regulations of steroidogenesis in gonad. Recently we have started to work on testicular aging in induced aged rat model.
Teaching Experience: Since January 2012 teaching Endocrinology, Animal Physiology, Developmental Biology, Tools and techniques in Biology, Bioinformatics, Fish Biology and Molecular Biology to PG students.
Employment
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Mizoram University Teaching and Research2012 - Present
Education
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Banaras Hindu University Ph.D.
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Banaras Hindu University M.Sc.
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Banaras Hindu University B.Sc. (H)
Projects & Funding
Projects & funding information is unavailable.
Publications (28)
- The Testicular Leptin System in Rats with Different Severity of Type 2 Diabetes Mellitus Save
- Effect of metformin on testicular expression and localization of leptin receptor and levels of leptin in the diabetic mice Save
- Heat‐induced changes in the expression and localisation of PGC‐1 α in the mice testis Save
- Dexamethasone mediated downregulation of PGC-1α and visfatin regulates testosterone synthesis and antioxidant system in mouse testis Save
- Estrogen and progesterone dependent expression of visfatin/NAMPT regulates proliferation and apoptosis in mice uterus during estrous cycle Save
- Influence of ferulic acid consumption in ameliorating the cadmium-induced liver and renal oxidative damage in rats Save
- Isolation, characterization, and therapeutic activity of bergenin from marlberry (Ardisia colorata Roxb.) leaf on diabetic testicular complications in Wistar albino rats Save
- Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model Save
- Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model Save
- Vitamin D3 treatment regulates apoptosis, antioxidant defense system, and DNA integrity in the epididymal sperm of an aged rat model Save