MB
Michael Barnes
Queen Mary University of London, GlaxoSmithKline (United Kingdom)
Research areas: Biochemistry, Genetics and Molecular Biology · Genetics · Genetic Associations and Epidemiology · Genetic Mapping and Diversity in Plants and Animals · Bioinformatics and Genomic Networks
0000-0001-9097-7381
Employment
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Queen Mary University of London Professor of Bioinformatics2012 - Present
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GlaxoSmithKline (United Kingdom) Team Leader1997 - 2010
Education
Education history is unavailable.
Projects & Funding
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MICA: Immune-Mediated Inflammatory Disease Biobanks in the UK (IMIDBio-UK) Medical Research Council2017 - 2021
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Maximising Therapeutic Utility for Rheumatoid Arthritis using genetic and genomic tissue responses to stratify medicines. Medical Research Council2014 - 2021
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MICA: Psoriasis Stratification to Optimise Relevant Therapy (PSORT) Medical Research Council2014 - 2018
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A Genome Wide Association study of Unipolar Depression Medical Research Council2008 - 2010
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A Genome Wide Association study of Unipolar Depression Medical Research Council2008 - 2010
Publications (123)
- Multi‐Trait GWAS Analyses of Blood Pressure Traits Provide Limited Gains in Locus Discovery or Polygenic Risk Score Performance Compared to Single‐Trait GWAS Save
- Population-scale drug target and variant prioritization with Varformer Save
- Sex differences in trajectories to cardio-renal and mental health outcomes following the onset of type 2 diabetes: An observational cohort study using multi-state analysis in the UK Clinical Practice Research Datalink Save
- Unraveling Emerging Data on Lipoprotein(a)-Driven Cardiovascular Disease via Multiomics: A Review Save
- Multidisciplinary prediction of running-related injuries using machine learning Save
- The hyperacute plasma proteome reports injury severity and defines distinct trauma endotypes Save
- The SjD Map: An interactive pathway tour into Sjögren’s disease signalling mechanisms Save
- A time-sequenced approach to machine learning prognostic modelling with implementation on running-related injury prediction Save
- AI approaches for the discovery and validation of drug targets Save
- Ethnic differences in early onset multimorbidity and associations with health service use, long-term prescribing, years of life lost, and mortality: A cross-sectional study using clustering in the UK Clinical Practice Research Datalink Save
- The benefits and pitfalls of machine learning for biomarker discovery Save
- The successes and challenges of harmonising juvenile idiopathic arthritis (JIA) datasets to create a large-scale JIA data resource Save
- visxhclust: An R Shiny package for visual exploration of hierarchical clustering Save
- GEOexplorer: an R/Bioconductor package for gene expression analysis and visualisation Save
- Meeting Report: Psoriasis Stratification to Optimize Relevant Therapy Showcase Save
- Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates Save
- Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study Save
- Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction Save
- M3C: Monte Carlo reference-based consensus clustering Save
- Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates Save