Malla Reddy Gannarapu, Ph.D.
University of Arizona, University of Denver, CSIR–Indian Institute Of Chemical Technology (CSIR-IICT), Osmania University, Yonsei University
Research areas: Chemistry · Organic Chemistry · Synthesis and Characterization of Heterocyclic Compounds · Synthesis and biological activity · Crystal structures of chemical compounds
0000-0001-9120-2502
About
• Ph.D. in Chemical science with eleven years of combined post-doctoral and industrial experiences that resulted 18 publications and two patent application.
• Peer Reviewer: Reviewed approximately 40 manuscripts for peer-reviewed journals in the fields of medicinal chemistry, organic chemistry, and drug discovery.
• Broad scientific experience in developing new synthetic methodologies, synthesis of heterocycles, multi-step organic synthesis, medicinal chemistry, fragment- and structure-based drug design, structure-activity relationship studies, transition-metal-catalyzed reactions and photochemical methodologies; excellent multidisciplinary communication.
• Experience in optimizing scalable processes for API manufacturing.
• Experience in leading collaborative projects toward accomplishing scientific goals.
Employment
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University of Arizona Research Scientist2026 - Present
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University of Arizona Postdoc2024 - 2026
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University of Denver Postdoc Researcher2021 - 2024
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Yonsei University Postdoc Researcher2020 - 2021
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Nagoya Institute of Technology Postdoc Researcher2018 - 2020
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Macleods Pharmaceuticals Ltd Senior research associate2015 - 2018
Education
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CSIR–Indian Institute Of Chemical Technology (CSIR-IICT) PhD2010 - 2015
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Osmania University Master of Science2007 - 2009
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Osmania University Bachelor of Science2003 - 2006
Projects & Funding
Projects & funding information is unavailable.
Publications (20)
- A Medicinal Chemistry-Centered Evaluation of AlphaFold 3 and Boltz-2 Across Diverse Binding Modalities Save
- Discovery of the SARS-CoV-2 Papain-Like Protease Inhibitor MR1-114: From Structure-Based Design to In Vivo Antiviral Efficacy Save
- FDA-Approved Fluorine-Containing Molecules in 2024: Significance, Synthesis, and Therapeutic Applications Save
- Substrate Divergent 4π/6π Electrocyclization of CF3-Quinolone Heterodendralenes Save
- Construction of poly-N-heterocyclic scaffolds via the controlled reactivity of Cu-allenylidene intermediates Save
- Two Catalytic Annulation Modes via Cu-Allenylidenes with Sulfur Ylides that Are Dominated by the Presence or Absence of Trifluoromethyl Substituents Save
- Synthesis of novel hydrazone and azole functionalized pyrazolo[3,4-b]pyridine derivatives as promising anticancer agents Save
- Synthesis of novel trifluoromethyl substituted furo[2,3- b ]pyridine and pyrido[3′,2′:4,5]furo[3,2- d ]pyrimidine derivatives as potential anticancer agents Save
- Synthesis of novel triazole functionalized pyridine derivatives as potential antimicrobial and anti-biofilm agents Save
- Synthesis of novel amide functionalized 2H-chromene derivatives by Ritter amidation of primary alcohol using HBF4·OEt2 as a mild and versatile reagent and evaluation of their antimicrobial and anti-biofilm activities Save
- Synthesis of novel 1-substituted triazole linked 1,2-benzothiazine 1,1-dioxido propenone derivatives as potent anti-inflammatory agents and inhibitors of monocyte-to-macrophage differentiation Save
- Synthesis of Novel Pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine Derivatives and Their Cytotoxic Activity Save
- Studies on Synthesis of Novel Triazole Tagged Pyrazole Fused Naphthalene 5-Thiazine-5,5-dioxide Derivatives, Their Antimicrobial, and Antioxidant Activity Save
- Synthesis, cytotoxicity, antimicrobial and anti-biofilm activities of novel pyrazolo[3,4-b]pyridine and pyrimidine functionalized 1,2,3-triazole derivatives Save
- Synthesis of novel 1,2-benzothiazine 1,1-dioxide-3-ethanone oxime N-aryl acetamide ether derivatives as potent anti-inflammatory agents and inhibitors of monocyte-to-macrophage transformation Save
- An Efficient Protocol for the Synthesis of Novel 1,2,3-Triazole Substituted 4H-Chromene Derivatives Save
- Studies on Synthesis of Novel Triazolalkyl Tagged Trifluoromethyl Substituted Pyrimidine Derivatives and their Evaluation for Cytotoxic Activity Save
- Synthesis of Novel Imidazo[1,2-a]pyrimidin-5(1H)-one Derivatives by Intramolecular Cycloisomerization of 2-Amino-3-alkynylpyrimidin-4(3H)-one in the Presence of Aqueous Base Save
- Studies on Synthesis of Novel Triazolalkyl Tagged Trifluoromethyl Substituted Pyrimidine Derivatives and their Evaluation for Cytotoxic Activity Save
- A facile strategy for the synthesis of highly substituted imidazole using tetrabutyl ammoniumbromide as catalyst Save