Prof. Dr. Krishnaswamy Balamurugan

About

Studies from Balamurugan’s lab revealed the impact of bacterial pathogenesis in a model host system (C. elegans) starting from the physiology, cellular and biochemical, transcriptomics, proteomics, metabolomics and on the health-span events such as aging, gut-microbiome, obesity.
His research findings revealed the conserved molecular events during pathogen interaction but also provided a handy tool to study aging, obesity and wound healing related phenomenon for future therapeutic applications.
Currently, his research focuses on metabolite-protein interactions and involvement of small RNAs during host-pathogen interactions.

Employment

• University of California Irvine Project Scientist
  2001 - 2006
• Alagappa University Professor

Education

• Alagappa University

Projects & Funding

Projects & funding information is unavailable.

Publications (81)

• Deep ocean bacterial metabolites improve host survival and modulate immune-associated responses in Caenorhabditis elegans during Pseudomonas pathogenesis
  Archives of Microbiology 2026 DOI: 10.1007/s00203-026-04914-6
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• A comprehensive review of Azadirachta indica (Neem): Exploring proximate composition, bioactive compounds, and prospects for antimicrobial activity
  Biochemistry and Biophysics Reports 2026 DOI: 10.1016/j.bbrep.2026.102730
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• Decoding Host–Pathogen Interactions Through Caenorhabditis elegans: A Narrative Case Study
  Advanced Gut & Microbiome Research 2026 DOI: 10.1155/agm3/7753118
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• Coupled dopamine and insulin signaling mediated transgenerational and multigenerational inheritance of adaptive traits in Caenorhabditis elegans upon parental training with Salmonella enterica Serovar Typhi
  Microbiology Spectrum 2025 DOI: 10.1128/spectrum.02575-24
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• Hydroxypropyl β-Cyclodextrin-Functionalized MoO3 Quantum Dots as a Multifunctional Probe for PGE2 Detection, Bioimaging, and Oxidative Stress Management in Inflammatory Diseases
  ACS Applied Nano Materials 2024 DOI: 10.1021/acsanm.4c00405
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• Cronobacter sakazakii infection implicates multifaceted neuro-immune regulatory pathways of Caenorhabditis elegans
  Molecular Omics 2023 DOI: 10.1039/D3MO00167A
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• A systematic review on impact of SARS-CoV-2 infection
  Microbiological Research 2023 DOI: 10.1016/j.micres.2023.127364
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• Distinct global metabolomic profiles of the model organism Caenorhabditis elegans during interactions with Staphylococcus aureus and Salmonella enterica Serovar Typhi
  Molecular Omics 2023 DOI: 10.1039/D3MO00040K
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• Expressing OsiSAP8, a Zinc-Finger Associated Protein Gene, Mitigates Stress Dynamics in Existing Elite Rice Varieties of the ‘Green Revolution’
  Sustainability 2022 DOI: 10.3390/su141610174
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• Metabolomics: small molecules that matter more
  Molecular Omics 2021 DOI: 10.1039/D0MO00176G
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