0000-0001-9375-6242 About
Simone Brogi is Associate Professor of Pharmacology at the Department of Pharmacy of University of Pisa. He leads the Computational Pharmacology and Toxicology Unit in the research group of Prof. Vincenzo Calderone. He graduated in 2005 in Biological Sciences from the University of Siena, where he also received his PhD in Pharmaceutical Sciences in 2010. From 2011 to 2019 he directed the Molecular Modeling Unit at the Department of Biotechnology, Chemistry and Pharmacy (University of Siena) in the research group of Prof. Giuseppe Campiani. From 2019 to 2021 he was Senior Researcher in Pharmacology at Department of Pharmacy of University of Pisa. His research activity, described in over 100 papers, is focused on computational approaches for drug discovery.
Employment
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University of Pisa Associate Professor2022 - Present
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University of Pisa Assistant Professor2019 - 2022
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Università degli Studi di Siena Research Fellow2011 - 2019
Education
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Università degli Studi di Siena PhD in pharmaceutical sciences2007 - 2010
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Università degli Studi di Siena MSc in Drug Design and Synthesis2007 - 2007
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Università degli Studi di Siena Dr in Biological Sciences2005 - 2005
Projects & Funding
Projects & funding information is unavailable.
Publications (162)
- Taginostat, a new quinolone-based HDAC6 inhibitor, promotes apoptosis of chronic lymphocytic leukemia cells in vitro and in vivo by activating STAT4 Save
- Second‐generation prokineticin PKR1 receptor agonists: Advancing cardioprotection against chemotherapy‐induced toxicity Save
- Dimeric Anthraquinone Rugulosin A Induces Apoptosis in Lung Adenocarcinoma and Targets PI3K/AKT/MAPK Pathways In Silico Save
- Quinazolinone-Based PqsR Modulators Suppress Quorum-Sensing–Driven Virulence in Pseudomonas aeruginosa Save
- Discovery of thieno[2,3-d]pyrimidine-based dual Aurora B/VEGFR-2 inhibitors with potent anticancer activity: molecular docking, mechanistic studies, and in vivo validation in a breast cancer model Save
- Plasminogen–cyclodextrin aerosol for ARDS: activity retention in simulated oxygen therapy and inflammation-triggered clot lysis Save
- Pharmacological Investigation of a Novel Resveratrol-like SIRT1 Activator Endowed with a Cardioprotective Profile Save
- DNA gyrase-inhibitory antimicrobial anthraquinone from the endophytic Sordariomycetes fungus Diaporthe perseae Save
- A virtual insight into mushroom secondary metabolites: 3D-QSAR, docking, pharmacophore-based analysis and molecular modeling to analyze their anti-breast cancer potential Save
- Novel Antiviral Agents: Synthesis, Molecular Modelling Studies and Biological Investigation, 2nd Edition Save