JX
Jun Xie
University of Massachusetts Boston
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Virus-based gene therapy research · RNA Interference and Gene Delivery · CRISPR and Genetic Engineering
0000-0001-9565-1567
Employment
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University of Massachusetts Boston Associate Professor
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (62)
- “Just right” AAV gene therapy for spinal muscular atrophy Save
- Control of lipid metabolism in chondrocytes is critical for skeletal growth Save
- In vivo adenine base editing ameliorates Dravet syndrome phenotypes in a mouse model Save
- A deep learning model trained on expressed transcripts across different tissue types reveals cell-type codon-optimization preferences Save
- BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease Save
- AAV-RNAi constructs promote DRG toxicity Save
- AAV5 Delivery of CRISPR/Cas9 Mediates Genome Editing in the Lungs of Young Rhesus Monkeys Save
- Potential limitations of microdystrophin gene therapy for Duchenne muscular dystrophy Save
- Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope Save
- Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope Save
- Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editingin vivo Save
- Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration Save
- Direct ITR-to-ITR Nanopore Sequencing of AAV Vector Genomes Save
- Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery Save
- Suppression of Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva Using AAV Gene Delivery Save
- AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice Save
- Paradoxical activation of SREBP1c and de novo lipogenesis by hepatocyte-selective ACLY depletion in obese mice Save
- Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes Save
- Adenine Base Editing in vivo with a Single Adeno-Associated Virus Vector Save
- Coagulation factor IX gene transfer to non-human primates using engineered AAV3 capsid and hepatic optimized expression cassette Save