SHASHIKANT BHANDARI
All India Shri Shivaji Memorial Society's College of Pharmacy, All India Shri Shivaji Memorial Society College of Pharmacy, AISSMS COLLEGE OF PHARMACY pune
About
SHORT RESUME OF PI DR. SHASHIKANT V BHANDARI
Name of PI Dr. Shashikant V, bhandari
Date of Birth 07/10/1974
Domain Expertise Molecular Modelling, ant-cancer, anti-tubercular, synthesis, Pharmaceutical chemistry
Number of articles in pubmed (past 10 years) 26
H-Index 13
Fellow of Academies Elsevier Academy, Netherland, Europe,
Member QSAR.ORG society.
Details of Publication related to the proposal:
Details of Patents: Indian Patent Office
1. Patent Title:SUBSTITUTED THIAZOLE COMPOUNDS AS ANTICANCER AGENTS
Applicants:Mrs. Sonali Sandeep Shinde, Dr. Aniket Sarkate, Dr. Dattatraya Pansare, Dr. Smita Pawar, Mr. Rajesh Yadala, Dr. Pravin Wakte, Dr. Shashikant Bhandari.Mr. Kalusing Padvi
Patent No.:544207 (Application no 202321072475)
Status:Granted in Force
2. Patent Title: Substituted diazole compounds as anticancer agents
Applicants: Shashikant V. Bhandari, Shital Patil
Patent No.: 202321039450
Status: Office Action
3. Patent Title: Substituted 3,5-Diaryl Pyrazoles compounds as anticancer agents
Applicants: Shashikant V. Bhandari, Aniket P. Sarkate
Patent No.: 20212100130 (dated 07/01/2021)
Status: Office Action
4. Patent Title: Substituted N-Phenyl 2,2–dichloro acetamide compounds as anticancer agents
Applicants: Shashikant V. Bhandari, Aniket P. Sarkate
Patent No.: 20212100002076 (dated 16/01/2021)
Status: Office Action
Title Impact factor of Journal Name of policy/programme/ protocol document or patent/commercialization of products where cited.
Inamdar, Poonam R, et al. “Applications of Samarium Complexes as Cytotoxic, Bioimaging and DNA Interacting Agents: A Comprehensive Review.” Reviews in Inorganic Chemistry, vol. 44, no. 3, 8 Mar. 2024, pp. 377–383, https://doi.org/10.1515/revic-2023-0026. Accessed 7 Dec. 2024.
4.1
Shinde, Sonali S, et al. “Computational and Synthetic Approach with Biological Evaluation of Substituted Thiazole Derivatives as Small Molecule L858R/T790M/C797S Triple Mutant EGFR Inhibitors Targeting Resistance in Non-Small Cell Lung Cancer (NSCLC).” Research Square (Research Square), 19 Feb. 2024, scite.ai/reports/computational-and-synthetic-approach-with-K6mdYdnp, https://doi.org/10.21203/rs.3.rs-3957730/v1. Accessed 7 Dec. 2024. Research square
Gore, V A, et al. “Synthesis, Characterization of Novel Thiazole Hydrazine Derivatives, and Inhibitory Action against the VEGFR-2.” Russian Journal of Bioorganic Chemistry, vol. 50, no. 2, 1 Apr. 2024, pp. 345–353, discovery.researcher.life/article/synthesis-characterization-of-novel-thiazole-hydrazine-derivatives-and-inhibitory-action-against-the-vegfr-2/60e2d1b797be3fc08b0bbb0bd74d6b33, https://doi.org/10.1134/s1068162024020067. Accessed 7 Dec. 2024. 1.1
Patil, Shital M, et al. “Molecular Modeling of Some 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors for the Treatment of Cancer.” Letters in Drug Design & Discovery, vol. 21, no. 10, 10 Apr. 2023, pp. 1694–1706, www.eurekaselect.com/article/130805, https://doi.org/10.2174/1570180820666230410083544. Accessed 7 Dec. 2024. 1.2
Tiwari, Shailee V., et al. “Appraisal and Synthesis of Novel Indole-Thiazole Derivatives as Epidermal Growth Factor Receptor Tyrosine Kinase (EGFR-TK) Inhibitors against Resistance Mutation for Lung Cancer Treatment.” Results in Chemistry, vol. 11, 30 Aug. 2024, p. 101760, www.sciencedirect.com/science/article/pii/S2211715624004569, https://doi.org/10.1016/j.rechem.2024.101760. Impact factor 2.3
Bhandari, Shashikant V., et al. “Molecular Docking, Pharmacokinetic and Molecular Simulation Analysis of Novel Mono‐Carbonyl Curcumin Analogs as L858R/T790M/C797S Mutant EGFR Inhibitors.” Chemistry & Biodiversity, vol. 20, no. 11, 26 Oct. 2023, https://doi.org/10.1002/cbdv.202301081. Accessed 27 Oct. 2024. 2.7
Patil, Shital M., and Shashikant V. Bhandari. “Optimization of Pharmacophore of Novel Hybrid Nucleus of 1,3,4-Oxadiazole-Chalcone Using Literature Findings and In-Silico Approach as EGFR Inhibitor.” Letters in Drug Design & Discovery, vol. 19, 14 Apr. 2022, https://doi.org/10.2174/1570180819666220414102310. Accessed 8 July 2022. Impact factor 1.15)
Patil, Shital, and Shashikant Bhandari. “A Review: Discovering 1,3,4-Oxadiazole and Chalcone Nucleus for Cytotoxicity
/ EGFR Inhibitory Anticancer Activity.” Mini-Reviews in Medicinal Chemistry, vol. 22, no. 5, Mar. 2022, pp. 805–820, https://doi.org/10.2174/1389557521666210902160644. Accessed 14 Nov. 2022. 3.86
Experience as Investigator:
SNo Title Role Funding Agentcy Amount Status
1 Design of Potential anti-inflammatory agents using molecular modeling studies. PI Minor/ S.P.P.University, Pune 1,50,000/ Completed, audited and Utilization certificate submitted.
2 Design of Potential anti-viral agents using molecular modeling studies. PI Minor/ S.P.P.Univ. Pune 1,95,000/-
3 Design of Potential anti-tubercular agents using molecular modeling studies. PI Minor/ S.P.P.Univ. Pune 2,20,000/-
Completed, audited and Utilization certificate submitted
4 To establish and implement the Entrepreneurship Development Cell activi
Employment
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All India Shri Shivaji Memorial Society's College of Pharmacy RESEARCHER ADVISOR FOR PG AND Ph.D./PROFESSOR1999 - Present
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All India Shri Shivaji Memorial Society College of Pharmacy RESEARCHER ADVISOR FOR PG AND Ph.D./PROFESSOR1999 - 2025
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All India Shri Shivaji Memorial Society College of Pharmacy Professor1999 - 2025
Education
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AISSMS COLLEGE OF PHARMACY pune M.pharm.Ph.D.2003 - 2010
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AISSMS COLLEGE OF PHARMACY pune M.pharm.Ph.D.2003 - 2010
Projects & Funding
Projects & funding information is unavailable.
Publications (25)
- Ferrocene tethered imidazoline NHC silver complex [FeMImiMeNHC-Ag] Catalyzed synthesis, anticancer activity, apoptosis, cell cycle arrest and in silico studies of new benzoxazoles Save
- Design and development of pyrazole–thiazole hybrid derivatives as anti-inflammatory and anti-oxidant agents Save
- Exploring Ionic Liquid-Based Methods in the Synthesis of Benzimidazole-1,3,4-Oxadiazole Derivatives for EGFR Inhibition, designed using a Comprehensive Molecular Docking and Dynamics Study Save
- Atom-based 3D-QSAR, pharmacophore modelling and molecular dynamics guided identification of thienopyrimidinone derivatives targeting EGFR in breast cancer Save
- Synthesis and Anticancer Activity of Diethyl (((5-(substituted phenyl)-1,3,4-thiadiazol-2-yl)amino)(quinolin-2-yl)methyl)phosphonate Save
- Rational Drug Discovery for Isoxazole Based VEGFR2 Inhibition Save
- Pharmacophore Optimization using Pharmacophore Mapping, QSAR, Docking, and ADMET Screening of Novel Pyrimidines Derivatives as Anticancer DNA Inhibitors Save
- Patenting Artificial Intelligence Based Technologies in Chemical and Pharmaceutical Sciences Save
- Design of Potential Curcumin Analogs as Anticancer Agents Using Molecular Modelling Tools Save
- Artificial Intelligence-Based Prediction of Drug Metabolism Save