CHITTARANJAN BEHERA, PhD
Research areas: Materials Science · Biomaterials · Nanoparticle-Based Drug Delivery · Advanced Drug Delivery Systems · RNA Interference and Gene Delivery
0000-0001-9705-5902
About
Dr. Chittaranjan Behera is a Postdoctoral Fellow at the Department of Clinical Haematology, Christian Medical College (CMC) Vellore, and at Roswell Park Comprehensive Cancer Center, Buffalo, USA. He has also served as an IISER-K PDF RA-I in the Department of Biological Sciences at the Indian Institute of Science Education & Research, Kolkata. He earned his PhD in Biotechnology (Pharmacology) jointly from Guru Nanak Dev University, Amritsar, and CSIR–Indian Institute of Integrative Medicine, Jammu. Prior to that, he completed his M.Tech in Biotechnology from Amity University, Noida and M.Sc in Biotechnology from GITAM University, Visakhapatnam, A.P., India.
Dr. Behera’s research primarily focuses on the pharmacology of active drugs, test molecules, and nanomedicine, with an emphasis on developing novel drug delivery systems, tumor-targeting strategies, and mechanism-based targeted drug delivery. He previously worked as a Junior Research Fellow (JRF) at CSIR-IIIM and is deeply passionate about advancing anticancer drug discovery. For more than eight years, he has been involved in extensive in vitro and in vivo anticancer drug screening, utilizing a variety of animal models, including mouse xenografts derived from human cancer cell lines.
He has also built strong expertise in drug combination therapy, employing mathematical models and isobologram analyses to target multiple oncogenic pathways. His work has led to the successful identification of several potent drug candidates that demonstrate promising outcomes in reducing tumor growth and improving survival. His academic excellence is reflected in multiple competitive qualifications, including CSIR/UGC JRF, ICAR SRF (PGS), GATE (2012 & 2015), and CUCET. Dr. Behera has made notable contributions to his field, with over 14 research articles in reputable journals, as well as a book chapter and a review article. He is also an active reviewer for several international scientific journals, including ACS Omega, RSC Advances (Royal Society of Chemistry), American Journal of Bioscience and Bioengineering and the Journal of Pharmaceutical Sciences. Recognizing cancer as the second leading cause of mortality worldwide after cardiovascular diseases, he is committed to advancing cancer research and therapeutics to positively impact the lives of millions affected by this disease.
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Publications (16)
- Mechanistic Approach into 1,2,3-triazoles-based IIIM(S)-RS98 Mediated Apoptosis in Lung Cancer Cells. Save
- Lipids and natural polymer based carrier systems for photodynamic therapy Save
- Development and characterization of Myrica esculenta plant extract-based albumin nanoparticles for anticancer activity Save
- Biodegradable nanocarrier of gemcitabine and tocopherol succinate synergistically ameliorates anti-proliferative response in MIA PaCa-2 cells Save
- Antifibrotic Agent Mediated Tumor Microenvironment Modulation and Improved Nanomedicine Delivery in Solid Tumor Save
- Redox-Responsive Hyaluronic Acid–Tacrolimus Conjugate: Synthesis, Characterization, and In Vitro Immunosuppressive Activity Save
- Implication of methylselenocysteine in combination chemotherapy with gemcitabine for improved anticancer efficacy Save
- Nisin and nisin-loaded nanoparticles: a cytotoxicity investigation Save
- Codelivery of Gemcitabine and MUC1 Inhibitor Using PEG-PCL Nanoparticles for Breast Cancer Therapy Save
- Mechanistic investigation of synergistic interaction of tocopherol succinate with a quinoline-based inhibitor of mammalian target of rapamycin Save
- Tumor micro-environment targeted collagenase-modified albumin nanoparticles for improved drug delivery Save
- Cyclodextrin nanosponges based site-retentive controlled release system for treatment of rheumatic arthritis Save
- Design, synthesis and comparative analysis of triphenyl-1,2,3-triazoles as anti-proliferative agents Save
- Spectrin conjugated PLGA nanoparticles for potential membrane phospholipid interactions: Development, optimization and in vitro studies Save
- Recent Advances in Formulation Strategies for Efficient Delivery of Vitamin D Save
- Antiproliferative efficacy of curcumin mimics through microtubule destabilization Save