Saptarshi Pyne

About

Assistant Professor, Dept. of Computational and Data Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, India 741246. Causal Reasoning, Bayesian Networks, Probabilistic Graphical Models, Network Biology, Gene Regulatory Network Inference.

Employment

• Indian Institute of Science Education and Research Kolkata Assistant Professor
  2024 - Present
• Indian Institute of Technology Jodhpur Assistant Professor
  2023 - 2024
• University of Wisconsin–Madison Postdoctoral Research Associate
  2020 - 2023
• Cognizant (United States) Programmer Analyst
  2010 - 2013

Education

• Indian Institute of Technology Guwahati PhD
  2014 - 2020
• Future Institute of Engineering and Management Bachelor of Technology (B. Tech)
  2006 - 2010

Projects & Funding

Projects & funding information is unavailable.

Publications (10)

• Uncovering Functional Gene Regulatory Networks in Bulk and Single-Cell Data through Robust Transcription Factor Activity Estimation and Model-Guided Experimental Validation
  2025 DOI: 10.1101/2025.06.09.658650
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• Inference of cell type-specific gene regulatory networks on cell lineages from single cell omic datasets
  Nature Communications 2023 DOI: 10.1038/s41467-023-38637-9
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• A network-based model ofAspergillus fumigatuselucidates regulators of development and defensive natural products of an opportunistic pathogen
  2023 DOI: 10.1101/2023.05.11.538573
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• Identifying strengths and weaknesses of methods for computational network inference from single-cell RNA-seq data
  G3 Genes|Genomes|Genetics 2023 DOI: 10.1093/g3journal/jkad004
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• Profiling Cell Type Specificity and Adverse Events of Genome Editing Nucleases in the Brain and Retina Using Single Cell Transcriptomics
  The 13th International Conference on Environmental Mutagens and 53rd Annual Meeting of the Environmental Mutagenesis and Genomics Society 2022 DOI: 10.1002/em.22502
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• Impact of the Continuous Evolution of Gene Ontology on the Performance of Similarity Measures for Scoring Confidence of Protein Interactions
  SN Computer Science 2020 DOI: 10.1007/s42979-020-00350-5
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• Rapid Reconstruction of Time-Varying Gene Regulatory Networks
  IEEE/ACM Transactions on Computational Biology and Bioinformatics 2020 DOI: 10.1109/tcbb.2018.2861698
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• Rapid Reconstruction of Time-varying Gene Regulatory Networks with Limited Main Memory.
  IEEE/ACM transactions on computational biology and bioinformatics 2019 DOI: 10.1109/tcbb.2019.2946826
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• Impact of the Continuous Evolution of Gene Ontology on Similarity Measures
  Lecture Notes in Computer Science 2019 DOI: 10.1007/978-3-030-34872-4_14
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• Rapid Reconstruction of Time-varying Gene Regulatory Networks
  2018 DOI: 10.1101/272484
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