Parthasarathi Ajitkumar

Employment

• Indian Institute of Science Professor & ICMR Emeritus Scientist
  1989 - Present

Education

• Indian Institute of Science PhD
  1977 - 1984

Projects & Funding

Projects & funding information is unavailable.

Publications (10)

• Complex, dynamic, and diverse phenotypes of stress/antibiotics-induced and natural subpopulations of Mycobacterium tuberculosis
  Tuberculosis 2026 DOI: 10.1016/j.tube.2026.102759
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• Percoll discontinuous density gradient centrifugation method for the fractionation of the subpopulations of Mycobacterium smegmatis and Mycobacterium tuberculosis from in vitro cultures
  MethodsX 2023 DOI: 10.1016/j.mex.2023.102344
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• Elevated Levels of Three Reactive Oxygen Species and Fe(II) in the Antibiotic-Surviving Population of Mycobacteria Facilitate De Novo Emergence of Genetic Resisters to Antibiotics
  Antimicrobial Agents and Chemotherapy 2022 DOI: 10.1128/aac.02285-21
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• Deletion of rifampicin-inactivating mono-ADP-ribosyl transferase gene of Mycobacterium smegmatis globally altered gene expression profile that favoured increase in ROS levels and thereby antibiotic resister generation
  Current Research in Microbial Sciences 2022 DOI: 10.1016/j.crmicr.2022.100142
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• The H2O2 inherently released by the mycobacterial minor subpopulation enhances the survival of the major kin subpopulation against rifampicin
  Current Research in Microbial Sciences 2022 DOI: 10.1016/j.crmicr.2022.100148
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• Genetic resisters to antibiotics in Escherichia coli arise from the antibiotic surviving population containing three reactive oxygen species
  FEMS Microbiology Letters 2021 DOI: 10.1093/femsle/fnab157
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• A method for the enrichment, isolation and validation of Mycobacterium smegmatis population surviving in the presence of bactericidal concentrations of rifampicin and moxifloxacin
  FEMS Microbiology Letters 2021 DOI: 10.1093/femsle/fnab090
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• Unique Mode of Cell Division by the Mycobacterial Genetic Resister Clones Emerging De Novo from the Antibiotic-Surviving Population
  mSphere 2020 DOI: 10.1128/mSphere.00994-20
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• Mycobacterium smegmatis moxifloxacin persister cells produce high levels of hydroxyl radical, generating genetic resisters selectable not only with moxifloxacin, but also with ethambutol and isoniazid
  Microbiology 2020 DOI: 10.1099/mic.0.000874
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• A Symmetric Molecule Produced by Mycobacteria Generates Cell-Length Asymmetry during Cell-Division and Thereby Cell-Length Heterogeneity
  ACS Chemical Biology 2018 DOI: 10.1021/acschembio.8b00080
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