AP

Amrita Patil

Symbiosis International University, Green Pyramid Biotech Pvt.Ltd, Pune Venture Centre, Pune, National Chemical Laboratory CSIR Biochemical Sciences Division, University of Mysore

ORCID iD 0000-0001-9894-2909
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About

Aug-2014 - Present
Ph.D. student at Biochemical sciences division ,CSIR-National Chemical Laboratory ,Pune, India.
PhD Thesis on “ Strategies for impeding quorum sensing in bacteria: Basic and applied aspects”
My doctoral work is focused on the current challenge of antimicrobial resistance (AMR). It involves biosynthesis of hydrophilic glycomonoterpenes from hydrophobic monoterpenes (Citral and Citronellal) to attenuate quorum sensing associated virulence in bacteria. Further, the mode of action of this active compound and its effect on quorum sensing related gene expression in P.aeruginosa was deciphered using realtime PCR. Along with this application of the same compound in implant coating is under study.
(Supervisor- Dr. Asmita Prabhune)
• Jan-2014-Jul 2014
Junior Research Fellow at Tissue Culture Section of Agriculture Division (VSI ),Pune on project funded by Department of Atomic Energy (DAE)/ BRNS in Collaboration with BARC, Mumbai.
Project title: “Use of irradiated chitosan as biostimulator for sugarcane and potato”
• Jun 2012-Jun 2013
M.Sc Dissertation on “Diversity analysis of Fusarium spp.from Sorghum bicolor by using ISSR markers”
• Jun 2010-Jun 2011
B.Sc. Dissertation on “Induction of somatic embryogenesis in Strychnos nux-vomica”
• Jun 2008-Jun 2009
PICC ( Pune Inter College Consortium) scholarship for Project-
Title: “Tissue culture studies on Vitis vinifera L.var. Pione”

Employment

  • Symbiosis International University Research Associate
    2020 - Present
  • Green Pyramid Biotech Pvt.Ltd, Pune Venture Centre, Pune Visiting Scientist
    2019 - 2019
  • Vasantdada Sugar Institute JRF
    2013 - 2014

Education

  • National Chemical Laboratory CSIR Biochemical Sciences Division Ph.D. Biological sciences
    2014 - Present
  • University of Mysore M.Sc.
    2011 - 2013
  • Savitribai Phule Pune University B.Sc.
    2008 - 2011

Projects & Funding

Projects & funding information is unavailable.

Publications (6)

  • Glycomonoterpene-Functionalized Crack-Resistant Biocompatible Silk Fibroin Coatings for Biomedical Implants
    ACS Applied Bio Materials 2019 DOI: 10.1021/acsabm.8b00515
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  • Biosynthesis of Glycomonoterpenes to Attenuate Quorum Sensing Associated Virulence in Bacteria
    Appl Biochem Biotechnol 2016
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  • Diverse profiles of N-acyl-homoserine lactones in biofilm forming strains of Cronobacter sakazakii
    2016
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  • Inhibition of quorum-sensing-mediated biofilm formation in Cronobacter sakazakii strains
    Microbiology 2016
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  • Biological activity of sophorolipids and their possible use as antiviral agents
    Folia microbiologica 2015
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  • Role of Extracellular Proteases in Biofilm Disruption of Gram Positive Bacteria with Special Emphasis on Staphylococcus aureus Biofilms
    Enzyme engineering 2015
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