Nisha Philip
University of Edinburgh, University of Glasgow, Duke University, Texas A&M University, Indian Institute of Technology
0000-0001-9901-1997
About
Nisha Philip is a lecturer at the Institute of Immunology and Infection Research, University of Edinburgh. She received her PhD (Pharmacology) at Duke University, Durham, USA. Her doctoral work with Tim Haystead examined the interaction of phosphorylation and ubiquitin pathways in Plasmodium falciparum. She utilized mass spectrometry and chemoproteomic tools to identify novel antimalarial targets in the parasite kinome. She did her NIH-postdoctoral fellowship with Ashley Chi at the Institute of Genomic Sciences and Policy, Duke University where her research explored the role of miRNAs in the host-pathogen interaction between the malarial parasite and red blood cells in sickle cell disease. Additionally, she examined the targets of these small RNAs in P. falciparum to elucidate the mechanism by which they affect the parasite. As an EMBO fellow with Andy Waters at the Wellcome Centre for Molecular Parasitology, Nisha studied signal transduction pathways required for malaria parasite infection and transmission. Recently she has developed powerful technologies for conditional protein regulation in the rodent malaria model, P. berghei, to examine roles of multifunctional enzymes during the parasite’s life cycle.
In September 2017, Nisha joined the Institute of Immunology and Infection Research at Edinburgh University. Her main interest is to understand how signalling networks are organised during host cell infection and host-to-vector transmission in the pursuit to identify simultaneous curative and transmission blocking strategies.
Employment
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University of Edinburgh Lecturer2018 - Present
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University of Edinburgh ISSF Fellow2017 - 2018
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University of Glasgow Research Associate2008 - 2017
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Duke University Postdoctoral fellow2007 - 2008
Education
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Duke University PhD2001 - 2007
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Texas A&M University M.S.1998 - 2000
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Indian Institute of Technology M.Sc.1996 - 1998
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University of Delhi B.Sc.1993 - 1996
Projects & Funding
Projects & funding information is unavailable.
Publications (20)
- A divergent cyclic nucleotide binding protein promotes Plasmodium ookinete infection of the mosquito Save
- A divergent cyclic nucleotide binding protein promotes Plasmodium ookinete infection of the mosquito Save
- Repositioning Brusatol as a Transmission Blocker of Malaria Parasites Save
- BioMalPar XX: looking back on, and forward from, 20 years of malaria research Save
- Unusually Divergent Ubiquitin Genes and Proteins in Plasmodium Species. Save
- The quest for control. Save
- Beyond phosphorylation: Putative roles of post-translational modifications in Plasmodium sexual stages Save
- Inducible developmental reprogramming redefines commitment to sexual development in the malaria parasite Plasmodium berghei. Save
- Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum. Save
- Stage-Specific Changes in Plasmodium Metabolism Required for Differentiation and Adaptation to Different Host and Vector Environments. Save