Sanhita Sinharay
Indian Institute of Science, The University of Texas MD Anderson Cancer Center, The University of Arizona, Indian Institute of Technology Madras, National Institutes of Health, Jadavpur University
About
Sanhita Sinharay completed her Masters from Indian Institute of Technology, IIT, Madras, Chennai, India in Chemistry and then Ph.D. from University of Arizona, Tucson, AZ, USA in the department of Chemistry and Biochemistry. During her Ph. D., she pioneered the development and translation of a class of non-metallic Chemical Exchange Saturation Transfer (CEST) Magnetic Resonance Imaging (MRI) contrast agents for enzyme activity detection within in vivo mouse models of ovarian, colon and pancreatic cancer. These studies evaluated the potential of these CEST MRI agents to non invasively monitor enzyme activity levels in tumors and correlate it to tumor aggressiveness, aid in optical surgical navigation and study responsiveness to chemotherapy drugs based on enzyme-inhibition. Following Ph.D., Sanhita did her post doctoral research in the area of neuroimaging of infectious diseases such as HIV, SIV, Cerebral Malaria, Ebola and Marburg at Radiology and Imaging Sciences department, Clinical Center, NIH, Bethesda, MD, USA. These studies focussed on the development of biomarkers and understanding of neuropathology of infectious diseases, often pre/-post-treatment methods with positron emission tomography (PET) and MRI. Following post doctoral research, Sanhita was a Junior Faculty (Research Instructor) at Cancer Systems Imaging, MD Anderson Cancer Center, Houston, TX, USA. Recently, Sanhita joined Indian Institute of Science, IISc Bangalore as an Assistant Professor and her lab focusses on development and translation of early biomarkers of cancer and neurodegenerative diseases using optoacoustic imaging and MRI methods.
Employment
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Indian Institute of Science Assistant Professor2021 - Present
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The University of Texas MD Anderson Cancer Center Research Instructor2019 - 2021
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National Institutes of Health Post Doctoral Researcher2016 - 2019
Education
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The University of Arizona Doctor of Philosophy2010 - 2016
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Indian Institute of Technology Madras Masters in Science2007 - 2009
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Jadavpur University Bachelors in Science2004 - 2007
Projects & Funding
Projects & funding information is unavailable.
Publications (25)
- Advanced Theranostics in a Pancreatic Cancer Model Integrating Dual Optoacoustic‐Photodynamic Performance of Asymmetric Zinc Phthalocyanines Save
- In Vivo Visualization of Tumor Metabolic Activity with a Tetra Glucose-Conjugated Zinc-Phthalocyanine Photoacoustic Contrast Save
- Neutrophil-Derived Extracellular Vesicles for Facile Delivery of Diagnostic Agents to Tumor Microenvironments Save
- Effect of PVP Molecular Weights on the Synthesis of Ultrasmall Cus Nanoflakes: Synthesis, Properties, and Potential Application for Phototheranostics Save
- Mapping Spatiotemporal Heterogeneity in Tumor Profiles by Integrating High-Throughput Imaging and Omics Analysis Save
- PET imaging of TSPO expression in immune cells can assess organ-level pathophysiology in high-consequence viral infections. Save
- Monitoring Immune Activation with Whole-Body Fluorodeoxyglucose-Positron-Emission Tomography in Simian Immunodeficiency Virus-Infected Rhesus Macaques. Save
- In vivo imaging of sterile microglial activation in rat brain after disrupting the blood-brain barrier with pulsed focused ultrasound: [18F]DPA-714 PET study. Save
- Trial of magnetic resonance-guided putaminal gene therapy for advanced Parkinson's disease. Save
- Neuroinflammatory Changes in Relation to Cerebrospinal Fluid Viral Load in Simian Immunodeficiency Virus Encephalitis. Save