0000-0001-9930-3287 About
Dr. Xing Wang is a bioengineer and biochemist at the University of Illinois at Urbana-Champaign (UIUC). His research group utilizes nucleic acids and protein engineering to evolve new molecular binders, and create and customize designer DNA nanostructure-based “plug-and-play” platforms for bioengineering and bionanotechnology applications centered on healthcare. He also has training in RNA-mediated genome programming and cellular engineering, and RNA chemistry and biology. Dr. Wang is the inventor of the DNA Star, DNA Net, DNA NanoGripper, and Cocktail Aptamer platforms and multivalent, pattern-recognition enabled strategy for disease diagnostics and therapeutics (Nat. Chem., 2020; Nat. Protoc., 2022; J. Am. Chem. Soc., 2023, 2024, 2025; Sci. Robot., 2024; Adv. Funct. Mater., 2025, 2026; Adv. Sci., 2025; Adv. Mater., 2026). He is a recipient of the Mikashi Award (Kleinmuntz Center) in 2021. He was selected as a fellow of Y Combinator Founder Cohort in 2021. Dr. Wang is a co-founder of a startup company, Atom Bioworks Inc., where he currently serves as a scientific advisor. His team's DNA Machine Demo was selected by TechCrunch as a best project in the Y Combinator’s W21 Demo Day event. He got a Spoke Award (CZ BioHub Chicago) in 2024. Dr. Wang's Nucleic Acids Programming Lab (NAPL) is well funded to support the research focusing on the creation and development of (1) effective therapeutic candidates and targeted drug/mRNA delivery platforms for cancer treatment and immunotherapy, as well as inhibition and prevention of viral infections, (2) ultrasensitive and inexpensive biosensors for rapid, simple, and amplification free disease diagnostics in point-of-care, self-testing, and laboratory-based high-throughput settings, (3) machine learning model, molecular docking, and molecular dynamic simulations pipeline to rapidly obtain new ligands for targeted drug delivery, and (4) molecular barcodes for multiplex and high resolution biosensing and imaging.
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Publications (86)
- DNA Nanotechnology for Effective Cancer Immunotherapy Save
- Geometry-dependent mRNA delivery with programmable RNA-DNA nanostructures Save
- Multi-dimensional DNA nanostructures isothermally assembled in hydrated ionic liquids Save
- Intranasal vaccines by precision printing Save
- Ultrasensitive Detection of Porcine Epidemic Diarrhea Virus Infections Using Multivalent DNA Nanostructure‐Enabled Lateral Flow Assay Save
- DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition Save
- DNA Origami‐Templated Aptamer Chiral Structures Realize Cellular Enantioselectivity Save
- Rapid and reusable high-throughput microfluidics through modular assembly Save
- AptaBLE: A Deep Learning Platform for Aptamer Generation and Analysis Save
- APIPred Web 1.0: A Web Platform to Predict Potential Aptamer Sequences for Protein targets Save
- Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes Save
- Engineering Two-Dimensional Nanobody-Origami Architectures for Enhanced Antiviral Activity Save
- DNA Nanostructure Self-Assembly in an Aqueous Ionic Liquid Solution with Enhanced Stability and Target Binding Affinity Save
- Engineering advanced functional nanomaterials for virus detection Save
- Probing millikelvin temperature sensitivity in chiral nanoparticles via optical forces Save
- Broad-Spectrum HIV-1 Detection and Neutralization via Multivalent Designer DNA Nanostructures Save
- Engineering Versatile Two-Dimensional Nanobody-Origami Architectures for Enhanced Antiviral Activity Save
- Photonic crystal enhanced fluorescence with DNA-based nano-gripper for ultrasensitive intact viral pathogen biosensing Save
- Engineering Novel DNA Nanoarchitectures for Targeted Drug Delivery and Aptamer Mediated Apoptosis in Cancer Therapeutics Save
- A biosensor-integrated filtration device for nanoparticle isolation and label-free imaging Save