Dhatchana Moorthy

Employment

• Karyon Bio Private Limited Principal Scientist
  2024 - Present
• EinNext Biosciences Senior Consultant
  2020 - 2024
• Orchid Chemicals and Pharmaceuticals Limited Research Scientist
  2008 - 2020
• Dabur Research Foundation Senior Research Scientist
  2004 - 2008
• Charité Universitätsmedizin Berlin Campus Benjamin Franklin Guest Scientist
  2001 - 2003
• Institute of Genomics and Integrative Biology CSIR Project assistant
  2001 - 2001

Education

• University of Madras Ph.D (Pharmaceutical Science - Biochemistry)
  2011 - 2019
• Institute of Technology Banaras Hindu University M.Pharmacy
  1998 - 2000
• Tamil Nadu Dr MGR Medical University B.Pharmacy
  1994 - 1998

Projects & Funding

Projects & funding information is unavailable.

Publications (22)

• A chimeric natriuretic peptide (Ev-NP) inhibits isoproterenol (ISO)-induced hypertrophic growth in in vivo and in vitro models by enhancing cGMP and its downstream signaling targets: In silico docking and binding efficacy analysis with NPR-A and NPR-B re…
  Peptides 2026 DOI: 10.1016/j.peptides.2026.171487
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• Cross-study transcriptomics and machine learning approaches reveal a predictive six-gene panel for hepatocellular carcinoma
  Medicine in Omics 2026 DOI: 10.1016/j.meomic.2026.100061
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• Expression and Regulation of Npr1 Gene Coding for Natriuretic Peptide Receptor-A in Hypertrophied Heart: Mechanisms and Therapeutic Implications
  International Journal of Peptide Research and Therapeutics 2026 DOI: 10.1007/s10989-026-10806-6
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• In silico design and development of benzyl piperazine conjugates for targeting choline esterase pathway in Alzheimer's disease
  In Silico Research in Biomedicine 2026 DOI: 10.1016/j.insi.2026.100315
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• Synthesis of 2-aryl/alkylaminomethyl 17-sulfamate/17-methyl estratrienes and their in vitro cytotoxicity in human cancer cell cultures
  Steroids 2026 DOI: 10.1016/j.steroids.2026.109778
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• Computational investigation and synthesis of 6-chlorocoumarin-oxadiazole hybrids for identifying newer candidates against Alzheimer's disease using multi-target strategies
  Letters in Drug Design & Discovery 2025 DOI: 10.1016/j.lddd.2025.100260
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• Integrative Machine Learning Approaches to Identify and Validate Gene Biomarkers for Early Detection of Hepatocellular Carcinoma
  2024 DOI: 10.21203/rs.3.rs-5720650/v1
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• An Efficient Synthesis of Novel Aminothiazolylacetamido-Substituted 3,5-Bis(arylidene)-4-piperidone Derivatives and Their Cytotoxicity Studies
  ACS Omega 2024 DOI: 10.1021/acsomega.4c00039
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• C-Type Natriuretic Peptide (CNP) Induces Cell Death and Sensitizes the Effect of Cisplatin in Human Non-small Cell Lung Cancer Cells (A549)
  International Journal of Peptide Research and Therapeutics 2022 DOI: 10.1007/s10989-022-10420-2
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• Divergent Synthesis and Evaluation of the in vitro Cytotoxicity Profiles of 3,4‐Ethylenedioxythiophenyl‐2‐propen‐1‐one Analogues
  ChemMedChem 2019 DOI: 10.1002/cmdc.201900225
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