DR BASIR AHMAD
Jamia Hamdard, Department of Atomic Energy, Government of India, Aligarh Muslim University, Aligarh Muslim University Faculty of Sciences, Michigan State University
About
Basir's research interests are primarily focused on the investigation of molecular mechanism of protein aggregation, which is the cause of many late-life diseases such as Alzheimer’s, Parkinson’s, cataracts and Type 2 diabetes. He has a particular interest in the development of drugs that can prevent aggregation. Since these diseases affect millions of people every year, he thinks that preventing aggregation is a public health priority. He earned his MSc and PhD degree in Biotechnology from Interdisciplinary Biotechnology Unit, AMU, Aligarh. During his PhD, he studied, at a molecular level, of the process by which native proteins convert into partially folded states, a necessary step to initiate aggregation. His post-doctoral works, performed in the field of protein aggregation and amyloid formation, were carried out at the University of Florence (Italy) for two years and Michigan State University (USA) for two years. He is the recipient of several National and International fellowships such as CSIR-JRF in 2002; EURAMY-Systemic Amyloidosis in Europe Postdoctoral Fellowship, Italy in 2007; Japan Society for the Promotion of Science (JSPS) Fellowship in 2010, USA National Science Foundation (NSF) postdoctoral fellowship in 2010 and UGC-Faculty position of University Grant Commission-Faculty Recharge Programme
(UGC-FRP) in 2013. During his postdoctoral fellowship at Michigan State University (USA), as a lead researcher of Prof Lisa Lapidus’ group, he discovered a new treatment path for Parkinson's disease. The results of his discovery were published in the Proceedings of the National Academy of Sciences, USA, and Journal of Biological Chemistry. His work on Parkinson’s disease attracted a high level of recognition in the scientific world and public media as well. The Faculty of 1000 (F1000) places his work among the top 2% of published articles in biology and medicine.
Employment
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Jamia Hamdard UGC-Assistant Professor2019 - Present
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Department of Atomic Energy, Government of India UGC-Assistant Professor2014 - 2019
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Department of Atomic Energy, Government of India Reader-F2013 - 2014
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Department of Atomic Energy, Government of India Visiting Scientist2012 - 2013
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Michigan State University Visiting Research Associate2010 - 2012
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Università degli Studi di Firenze Postdoctoral Fellow2007 - 2009
Education
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Aligarh Muslim University PhD2002 - 2007
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Aligarh Muslim University MSc1999 - 2002
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Aligarh Muslim University Faculty of Sciences BSc1996 - 1999
Projects & Funding
Projects & funding information is unavailable.
Publications (72)
- Cytotoxicity originates at the amorphous intermediate stage during amyloid-like oligomerization of serum albumin under mild denaturing conditions Save
- Perfluorohexane sulfonate (PFHxS) modulates conformational transitions, ligand-binding functions and aggregation of human serum albumin Save
- Carglumic acid and mesalazine as potential anti-mycobacterial agents: a spectroscopic study for repurposing drugs against Mycobacterium tuberculosis targeting its essential enzyme ThyX Save
- A cobalt coordination complex binds on a unique binding site between domain-I and domain-III of serum albumin Save
- Redesigning the kinetics of lysozyme amyloid aggregation by cephalosporin molecules Save
- Off-target molecular recognition of cyproterone acetate by human lysozyme: conformational remodelling, enzyme modulation, and amyloid inhibition Save
- Dietary protein deficiency exacerbates perfluorohexane sulfonate (PFHxS)-induced reproductive abnormalities and metabolic disruptions in female rats Save
- Developmental and neurobehavioral toxicity of di-(2-ethylhexyl) phthalate (DEHP) in zebrafish larvae Save
- Conformational constraints and ligand interactions are key determinants of the distinct aggregation pathways observed in human serum albumin Save
- Biophysical Evidence for the Amyloid Formation of a Recombinant Rab2 Isoform of Leishmania donovani Save