MH
0000-0002-0266-1414 Employment
Employment history is unavailable.
Education
Education history is unavailable.
Projects & Funding
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Trial of Repurposed Unithiol for snakebite Envenoming Phase 1 Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in health Kenyan Adults Cures Within Reach2022 - 2023
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Rapid review of Interventions to Save Newborn LivEs Bill and Melinda Gates Foundation2021 - 2026
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Establishing Shigella Human Infection Studies in an endemic population in Kenya for evaluating Shigella vaccines Wellcome Trust2021 - 2026
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APhase 1b/II trial to evaluate the safety, immunogenicity and efficacy of ChAdOx1 nCoV-19 vaccine against COVID-19 in Kenya University of Oxford2020 - 2023
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MICA: Hydroxyurea - Pragmatic Reduction In Mortality and Economic burden (H-PRIME) Medical Research Council2019 - 2024
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A Safety and Immunogenicity of a Shigella-tetravalent bioconjugate vaccine: A phase 1 /2 randomised controlled and age descending study including dose finding in 9-month-old infants LimmaTech Biologics Ag2018 - 2023
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A Phase III randomised controlled multi-centre trial to evaluate the efficacy of the R21/Matrix-M vaccine in African children against clinical malaria University of Oxford
Publications (82)
- Strengthening sustainable clinical trial models for greater health impact: Expert discussion from the Annual Wellcome Major International Programme Regional Meeting 2024 [version 1; peer review: awaiting peer review] Save
- Severe Malaria A Research and Trials consortium - Multisite Adaptive Platform (SMAART MAP) Trial Protocol [version 1; peer review: 1 approved] Save
- Six ways to empower African research and development for health Save
- Pf8: an open dataset of Plasmodium falciparum genome variation in 33,325 worldwide samples [version 1; peer review: 3 approved] Save
- Establishing laboratory reference ranges for haematological and biochemical blood parameters in adults and children in Kilifi, Kenya [version 1; peer review: 2 approved with reservations] Save
- A pragmatic randomized controlled trial of standard care versus corticosteroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals (SONIA) [version 2; peer review: 3 approved] Save
- Replication Data for: Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults Save
- Establishing laboratory reference ranges for adults and children in Kilifi, Kenya Save
- SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART) Save
- Nutritional supplementation in children with severe pneumonia in Uganda and Kenya (COAST-Nutrition): a phase 2 randomised controlled trial Save
- A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial) [version 1; peer review: 2 approved] Save
- (Extended Data) Amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial Save
- Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol Save
- Where Do Those Data Go? Reuse of screening results from clinical trials to estimate population prevalence of HBV infection in adults in Kilifi, Kenya Save
- Where Do Those Data Go? Reuse of screening results from clinical trials to estimate population prevalence of HBV infection in adults in Kilifi, Kenya Save
- Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial [version 2; peer review: 3 approved] Save
- SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART) [version 1; peer review: 1 approved, 2 approved with reservations] Save
- Safety and immunogenicity of varied doses of R21/Matrix-M™ vaccine at three years follow-up: A phase 1b age de-escalation, dose-escalation trial in adults, children, and infants in Kilifi-Kenya [version 1; peer review: 2 approved] Save
- Immunogenicity and safety of fractional doses of 17D-213 yellow fever vaccine in HIV-infected people in Kenya (YEFE): a randomised, double-blind, non-inferiority substudy of a phase 4 trial Save
- Immunogenicity and safety of fractional doses of 17D-213 yellow fever vaccine in HIV-infected people in Kenya (YEFE): a randomised, double-blind, non-inferiority substudy of a phase 4 trial Save