Fred Friedman

Employment

• Fred Friedman LLC

Education

• Columbia University Ph.D.
  ? - 1979

Projects & Funding

Projects & funding information is unavailable.

Publications (121)

• Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping
  Toxicological Sciences 2013 DOI: 10.1093/toxsci/kft143
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• Site-specific phosphorylation of raf in cells containing oncogenic ras-p21 is likely mediated by jun-N-terminal kinase
  Annals of Clinical and Laboratory Science 2008
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• Two peptides derived from ras-p21 induce either phenotypic reversion or tumor cell necrosis of ras-transformed human cancer cells
  Cancer Chemotherapy and Pharmacology 2008 DOI: 10.1007/s00280-007-0630-5
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• The dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type-but not by oncogenic-ras-p21 protein
  Frontiers in Bioscience 2007 DOI: 10.2741/2550
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• PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo
  International Journal of Cancer 2006 DOI: 10.1002/ijc.22029
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• Rapid confomational dynamics of cytochrome P450 2E1 in a natural biological membrane environment
  Biochemistry 2006 DOI: 10.1021/bi061873u
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• Functional interactions of raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic ras signaling pathway
  Biochemistry 2005 DOI: 10.1021/bi050619j
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• An effector peptide from glutathione-S-transferase-pi strongly and selectively blocks mitotic signaling by oncogenic ras-p21
  Protein Journal 2004 DOI: 10.1023/B:JOPC.0000026419.54902.bb
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• Comparison of molecular dynamics averaged structures for complexes of normal and oncogenic ras-p21 with SOS nucleotide exchange protein, containing computed conformations for three crystallographically undefined domains, suggests a potential role of thes…
  Protein Journal 2004 DOI: 10.1023/B:JOPC.0000026417.72621.1f
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• Immunochemical Analysis of Chromatin
  Methods in Enzymology 2004 DOI: 10.1016/S0076-6879(03)76014-5
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