Malcolm West
University Hospital Southampton NHS Foundation Trust, University of Southampton, University of Malta
Research areas: Medicine · Oncology · Enhanced Recovery After Surgery · Colorectal Cancer Surgical Treatments · Cardiac, Anesthesia and Surgical Outcomes
About
Associate Professor Malcolm West was appointed to the University of Southampton in 2022 as Associate Professor in Colorectal Surgery and Prehabilitation Medicine and is an Honorary Consultant Colorectal and Advanced Malignancy Surgeon at University Hospitals Southampton NHS Foundation Trust.
NIHR-funded since 2011, he trained as a clinical academic in Liverpool and Wessex, completing a PhD in exercise physiology, perioperative risk stratification, and prehabilitation for advanced rectal cancer. He has held various NIHR clinical academic awards and senior fellowships including the Royal College of Surgeons Senior Fellowship in advanced and robotic colorectal cancer surgery at St Mark’s Hospital, London.
Within the Southampton BRC he leads a translational research programme to improve perioperative and long-term outcomes after major surgery, focusing on risk assessment and multimodal prehabilitation. His work explores the relationship between fitness, body composition, and tumour immune microenvironment.
Malcolm co-chairs the NIHR Research for Patient Benefit programme (Southern England), co-leads the new National Clinical Audit of Perioperative Care and is the Wessex Cancer Alliance Lead for Early Diagnostics in Colorectal Cancer and is the Southampton BRC Academic Clinical Development Lead. He supervises multiple postgraduate research students across the UK.
Employment
Education
- 2000 - 2005
Projects & Funding
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REMACS - Understanding the impact of perineal Reconstruction after Extended MArgin Cancer Surgery on longer-term quality of life, morbidity and health economic outcomes a prospective longitudinal cohort study National Institute for Health and Care Research2025 - 2028
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Understanding the interactions between resilience, immune ecology, metabolism and tumour outcomes in advanced cancer patients receiving immunotherapy – ImmunoFIT NIHR Oncology- TRC
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Preoperative optimisation of modifiable risk factors in surgery of the pancreas – PROMISE-P Rising Tide Foundation for Clinical Cancer Research
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The effectiveness of resistance exercise prehabilitation for preventing muscle wasting and improving patient outcomes during treatment for Oesophageal and Gastric cancers NorthWest Cancer Research Charity
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Understanding the mechanisms of resilience, body composition and tumour outcomes with cancer therapies and multimodal prehabilitation interventions in advanced cancer patients. Royal Marsden Cancer Charity
Publications (122)
- Development of consensus-based standards for a National Clinical Audit of Perioperative Care: protocol for a modified Delphi consensus study Save
- World Prehabilitation Day: advancing surgical optimisation beyond proof of concept Save
- Understanding the impact of perineal reconstruction after extended margin cancer surgery on longer-term quality of life, morbidity and health economic outcomes: protocol for the UK REMACS observational cohort study Save
- International validation of the Locally Recurrent Rectal Cancer—Quality of Life (LRRC-QoL) patient reported outcome measure Save
- ASO author reflections: the right care, for the right patient, at the right time: development of the PREdiCT screening tool for prehabilitation in cancer surgery Save
- Expert consensus on self-reported physical, nutritional, and psychological screening tools for prehabilitation in gastrointestinal cancer surgery: an international Delphi study Save
- Development of a core screening, assessment and outcome set for cancer prehabilitation: an international Delphi consensus study protocol Save
- Standards for reporting research methods, interventions, and Outcomes in Surgical Prehabilitation studies (SOS-Prehab) Save
- Perioperative risk assessment using cardiopulmonary exercise testing: supporting shared decision-making and prehabilitation Save
- Gain of visceral adipose tissue rather than low skeletal muscle mass is associated with overall survival in patients with colorectal liver metastases; results from the NewEPOC study Save
- Prospective case-control cohort analysis of two-day/two-stage pelvic exenteration surgery: safety, feasibility, acceptability and medium-term outcomes Save
- Physical fitness and body composition assessments in advanced cancer patients undergoing exenterative surgery - a pilot cohort study Save
- Development of a clinical core outcome set to evaluate lung cancer rehabilitation Save
- Opening the operating theatre to oncology: treatment of locally recurrent rectal cancer with peritoneal metastasis by simultaneous hyperthermic intraperitoneal chemotherapy and intraoperative electron beam radiotherapy Save
- [Correction] Protective ileostomy creation after anterior resection of the rectum (PICARR): a decision-making exploring international survey Save
- Head-down tilt lithotomy position and well-leg compartment syndrome: an international survey of current practice Save
- Intravenous Iron for Perioperative Anaemia in Colorectal Cancer Surgery: A Nested Cohort Analysis Save
- Protective ileostomy creation after anterior resection of the rectum (PICARR) Save
- Intraoperative electron radiotherapy (IOERT) in colorectal cancer: Updated systematic review of techniques, oncological outcomes and complications Save
- The Impact of Prehabilitation on Patient Outcomes in Oesophagogastric Cancer Surgery: Combined Data from Four Prospective Clinical Trials Performed Across the UK and Ireland Save