Surya Prakash Goud Ponnam

About

I am a human geneticist and a synthetic biologist. I have been working in the field of human molecular genetics for more than a decade and trying to understand the molecular mechanics responsible for important ophthalmic diseases including Pediatric Cataracts, Keratoconus, Macular Corneal Dystrophy etc. Our groups have gradually moved into genome editing. Besides these, we are also trying to understand the role of various molecular factors that are responsible for various other human diseases including PCOS.

Employment

• Tezpur University ASSISTANT PROFESSOR (STAGE-III)
  2019 - Present
• Tezpur University Assistant Professor-Stage II
  2014 - 2019
• Tezpur University Assistant Professor-Stage I
  2010 - 2014

Education

• L V Prasad Eye Institute Ph.D.
  2004 - 2010
• University of Hyderabad M.Sc.
  2002 - 2004
• Osmania University Nizam College B.Sc.
  2000 - 2002

Projects & Funding

Projects & funding information is unavailable.

Publications (9)

• Knockdown of XRCC5 and XRCC6 activity using CRISPR/Cas9 technology enhances homology-directed DNA repair at the CHST6 locus in HEK293 cells
  Experimental Eye Research 2026 DOI: 10.1016/j.exer.2026.111165
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• Evaluation of CRISPR-Cas9 mismatch activity using a BRET-based reporter system
  Microchemical Journal 2025 DOI: 10.1016/j.microc.2024.112256
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• Genetics and Epigenetics of Polycystic Ovary Syndrome
  Polycystic Ovary Syndrome - Symptoms, Causes and Treatment 2023
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• A comprehensive molecular genetic analysis of keratoconus patients from assam, a northeastern state of India.
  European journal of ophthalmology 2022 DOI: 10.1177/11206721221087551
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• Development of a Reporter System to Explore MMEJ in the Context of Replacing Large Genomic Fragments.
  Molecular therapy. Nucleic acids 2018 DOI: 10.1016/j.omtn.2018.03.010
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• Mutational screening of Indian families with hereditary congenital cataract.
  Molecular vision 2013
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• A cataract-causing connexin 50 mutant is mislocalized to the ER due to loss of the fourth transmembrane domain and cytoplasmic domain.
  FEBS open bio 2012 DOI: 10.1016/j.fob.2012.11.005
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• A missense mutation in LIM2 causes autosomal recessive congenital cataract.
  Molecular vision 2008
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• Mutation of the gap junction protein alpha 8 (GJA8) gene causes autosomal recessive cataract.
  Journal of medical genetics 2007 DOI: 10.1136/jmg.2007.050138
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