Employment
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Weill Cornell Medicine Postdoctoral Associate2024 - Present
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Virginia Commonwealth University Post-doctoral research fellow2022 - 2024
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (27)
- Structure-Guided Optimization of CHI3L1 Modulators Reveals G721–0377 as a Lead Compound for Restoring Astrocyte Function in Alzheimer’s Disease Save
- Restoring amyloid clearance: Z17 promotes astrocytes to clear Alzheimer's plaques via CHI3L1 inhibition Save
- Structure-Guided Discovery of CHI3L1 Inhibitors from Ultralarge Chemical Spaces for Glioblastoma Therapy Save
- Structure‐Based Virtual Screening Identifies TREM2‐Targeted Small Molecules that Enhance Microglial Phagocytosis Save
- Discovery of a CHI3L1-targeted small molecule modulating neuroinflammation in Alzheimer's disease via DNA-encoded library (DEL) screening Save
- Structural optimization of CHI3L1 inhibitors with improved pharmacokinetics and functional activity in 3D glioblastoma models Save
- Virtual Screening-Guided Discovery of Small-Molecule CHI3L1 Inhibitors with Functional Activity in Glioblastoma Spheroids Save
- Affinity Selection–Mass spectrometry coupled with biophysical validation enables proof-of-concept discovery of CHI3L1 binders Save
- CD28 and ICOS in immune regulation: Structural insights and therapeutic targeting Save
- Biological and therapeutic significance of targeting NLRP3 inflammasome in the brain and the current efforts to develop brain-penetrant inhibitors Save