Soumya Joseph

Employment

• RexCelTech Co-founder
  2026 - Present
• The University of Iowa Postdoc
  2016 - 2025
• Australian National University postcdoc
  2014 - 2016
• University of Sydney TA
  2009 - 2014

Education

• The University of Sydney Bachelor of Science Adv. (Hons.)
  2005 - 2008

Projects & Funding

Projects & funding information is unavailable.

Publications (13)

• LARGE1 processively polymerizes length-controlled matriglycan on prodystroglycan
  Nature Communications 2025 DOI: 10.1038/s41467-025-64080-z
  +Save
• Identification of a short, single site matriglycan that maintains neuromuscular function in the mouse
  2023 DOI: 10.1101/2023.12.20.572361
  +Save
• Deep Mutational Scanning in Disease-related Genes with Saturation Mutagenesis-Reinforced Functional Assays (SMuRF)
  2023 DOI: 10.1101/2023.07.12.548370
  +Save
• Dystroglycan N-terminal domain enables LARGE1 to extend matriglycan on α-dystroglycan and prevents muscular dystrophy
  2022 DOI: 10.1101/2022.08.09.502851
  +Save
• Structure and mechanism of LARGE1 matriglycan polymerase
  2022 DOI: 10.1101/2022.05.12.491222
  +Save
• POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan.
  eLife 2020 DOI: 10.7554/elife.61388
  +Save
• Clinical utility of RNA sequencing to resolve unusual GNE myopathy with a novel promoter deletion.
  Muscle & nerve 2019 DOI: 10.1002/mus.26486
  +Save
• Structural and biophysical analyses of the skeletal dihydropyridine receptor β subunit β1a reveal critical roles of domain interactions for stability.
  The Journal of biological chemistry 2017 DOI: 10.1074/jbc.m116.763896
  +Save
• The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.
  PloS one 2014 DOI: 10.1371/journal.pone.0109108
  +Save
• Synthesis of peptides and glycopeptides with polyproline II helical topology as potential antifreeze molecules.
  Bioorganic & medicinal chemistry 2013 DOI: 10.1016/j.bmc.2013.02.025
  +Save