XS
Xueyi Shen
University of Edinburgh, University of Edinburgh Division of Psychiatry
Research areas: Biochemistry, Genetics and Molecular Biology · Genetics · Genetic Associations and Epidemiology · Treatment of Major Depression · Epigenetics and DNA Methylation
0000-0002-0538-4774
Employment
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University of Edinburgh Senior Research Fellow2025 - Present
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University of Edinburgh Research Fellow2019 - 2025
Education
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University of Edinburgh Division of Psychiatry2015 - 2019
Projects & Funding
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CHECKPOINT: Finding immune & metabolic pathways to SMI Medical Research Council2024 - 2029
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Exploiting genomic approaches to identify the environmental basis of depression Wellcome Trust Ltd2021 - 2027
Publications (120)
- Convergent proteogenomic evidence prioritises five causal proteins and new drug targets for major psychiatric disorders Save
- Integrating Multi-Omics Summary Data Identifies Candidate Molecular Mechanisms for Major Depression Save
- Structural connectivity associations with dyslexia-linked genes identifies the left insula as the key phonological hub Save
- Association between polygenic risk for Major Depression and brain structure in a mega-analysis of 50,975 participants across 11 studies Save
- A methylome-wide association study of major depression with out-of-sample case–control classification and trans-ancestry comparison Save
- Limitations and Potential of Polygenic Risk Scores for Major Psychiatric Disorders Save
- Assessing a prediction model for depression risk using an early adolescent sample with self-reported depression Save
- Associations between IL-6 and trajectories of depressive symptoms across the life course: Evidence from ALSPAC and UK Biobank cohorts Save
- Data Resource Profile: Whole-Blood DNA Methylation Resource in Generation Scotland (MeGS) Save
- Epigenetic and Structural Brain Aging and Their Associations With Major Depressive Disorder Save
- Insights from a methylome-wide association study of antidepressant exposure Save
- Lifestyle, Early-life, and Genetic Health Risk Factors Underlying the Brain Age Gap: A Mega-Analysis Across 3,934 Individuals from the ENIGMA MDD Consortium Save
- Longitudinal associations between air pollution and incident dementia as mediated by MRI-measured brain volumes in the UK Biobank Save
- Multi-ancestry epigenome wide association study of generalized anxiety disorder Save
- Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies Save
- Antidepressant Exposure and DNA Methylation: Insights from a Methylome-Wide Association Study Save
- A comprehensive hierarchical comparison of structural connectomes in Major Depressive Disorder cases v. controls in two large population samples Save
- An epidemiological study of season of birth, mental health, and neuroimaging in the UK Biobank Save
- Comprehensive assessment of sleep duration, insomnia, and brain structure within the UK Biobank cohort Save
- Data Resource Profile: Whole Blood DNA Methylation Resource in Generation Scotland (MeGS) Save