SB
Shylesh Bhaskaran
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Muscle Physiology and Disorders · Mitochondrial Function and Pathology · Nutrition and Health in Aging
0000-0002-0651-2299
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Publications (30)
- iPLA2β: A novel store-operated calcium entry modulator contributing to muscle dysfunction during denervation Save
- Impact of Mlkl or Ripk3 deletion on age-associated liver inflammation, metabolic health, and lifespan. Save
- Reactive oxygen species in the pathogenesis of sarcopenia. Save
- The nitrone compound OKN-007 delays motor neuron loss and disease progression in the G93A mouse model of amyotrophic lateral sclerosis. Save
- Neuroprotective treatment with the nitrone compound OKN-007 mitigates age-related muscle weakness in aging mice. Save
- Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis. Save
- Inhibition of ATR Reverses a Mitochondrial Respiratory Insufficiency. Save
- Age Related Changes in Muscle Mass and Force Generation in the Triple Transgenic (3xTgAD) Mouse Model of Alzheimer's Disease. Save
- Restoration of Sarcoplasmic Reticulum Ca2+ ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice. Save
- Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice. Save
- Molecular changes associated with spinal cord aging. Save
- Disparate Central and Peripheral Effects of Circulating IGF-1 Deficiency on Tissue Mitochondrial Function. Save
- Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching. Save
- Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness. Save
- Oxidative stress-induced dysregulation of excitation-contraction coupling contributes to muscle weakness. Save
- Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. Save
- A fish oil diet induces mitochondrial uncoupling and mitochondrial unfolded protein response in epididymal white adipose tissue of mice. Save
- A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse. Save
- Muscle fiber type diversification during exercise and regeneration. Save
- Down-regulation of the mitochondrial matrix peptidase ClpP in muscle cells causes mitochondrial dysfunction and decreases cell proliferation. Save