Ajay Mili
Amity University Bengaluru, Manipal Academy of Higher Education, KLE Society's College of Pharmacy, Regional Institute of Pharmaceutical Sciences and Technology
About
I recently completed my Ph.D. in Pharmaceutical Sciences from Manipal Academy of Higher Education, India. My doctoral research focused on the in silico and preclinical evaluation of sesamol and its derivatives as potential hepatoprotective agents, particularly targeting NRF2-mediated cytoprotective pathways in drug-induced liver injury (DILI). This work combined computational drug design, synthesis, and biological evaluation to explore novel therapeutic candidates from natural product scaffolds.
Throughout my academic journey, I have developed a broad skill set spanning both computational and experimental pharmacology. I have hands-on experience in molecular docking, virtual screening, ADMET/toxicity prediction, organic synthesis, and structural characterization using FTIR, LC-MS, and NMR techniques. I have also conducted extensive in vivo studies in rodent models, including biochemical, histopathological, and oxidative stress analyses.
My research interests are interdisciplinary and include: Drug discovery and development from natural products and synthetic analogs, Hepatoprotection and drug-induced organ toxicity (liver, kidney, etc.), Oxidative stress, inflammation, and redox signaling pathways, NRF2, NF-κB, and other cellular defense mechanisms, Preclinical pharmacology and toxicology, Translational research focusing on bench-to-bedside approaches, In silico drug design including molecular docking, pharmacophore modeling, and QSAR, Target-based drug discovery in the areas of metabolic diseases and organ protection, Phytochemistry and bioactive compounds from traditional medicines, and Biomedical research writing and critical review
Alongside research, I’ve contributed to scientific publications, peer-reviewed articles, and academic presentations. I have also been involved in manuscript reviewing and enjoy engaging with research communication. I am passionate about exploring new frontiers in drug safety, pharmacological screening, and molecular mechanisms of therapeutic agents.
I am currently seeking postdoctoral opportunities where I can contribute my skills and continue to grow as a multidisciplinary researcher in pharmacology, toxicology, and translational science.
Employment
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Amity University Bengaluru Assistant Professor-12026 - Present
Education
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Manipal Academy of Higher Education Ph.D.2020 - 2025
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KLE Society's College of Pharmacy M. Pharm2016 - 2018
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Regional Institute of Pharmaceutical Sciences and Technology B. Pharm2012 - 2016
Projects & Funding
Projects & funding information is unavailable.
Publications (9)
- NETWORK PHARMACOLOGY BASED COMPUTATIONAL STUDY TO INVESTIGATE THE POTENTIAL MECHANISM OF SYZYGIUM CARYOPHYLLATUM AGAINST COLON CANCER Save
- Computational design, synthesis, in vitro and in vivo evaluation of a 3,4-methylenedioxyphenol (sesamol) derivative as an NRF2/HO-1 pathway activator for protection against drug-induced liver injury Save
- Identifying the role of Phytomolecules in the management of liver diseases by modulating NRF2 pathway: A Scoping Review Protocol Save
- Identifying the role of Phytomolecules in the management of liver diseases by modulating NRF2 pathway: A Scoping Review Protocol Save
- A computational study to identify Sesamol derivatives as NRF2 activator for protection against drug-induced liver injury (DILI) Save
- Identification of Phytomolecules as Isoform and Mutation specific PI3K-α inhibitor for protection against Breast Cancer using e-Pharmacophore modeling and Molecular dynamics simulations Save
- Identification of phytomolecules as isoform and mutation specific PI3K-α inhibitor for protection against breast cancer using e-pharmacophore modeling and molecular dynamics simulations Save
- Molecular docking and dynamics guided approach to identify potential anti-inflammatory molecules as NRF2 activator to protect against drug-induced liver injury (DILI): a computational study Save
- A comprehensive review on Sesamum indicum L.: Botanical, ethnopharmacological, phytochemical, and pharmacological aspects Save