Sharon Miracle Nayagam

About

I use mass spectrometry–based proteomics and translational multi-omics approaches to identify biomarkers and characterize molecular mechanisms underlying musculoskeletal and inflammatory diseases.

Employment

• Columbia University in the City of New York Staff Associate II
  2024 - 2025
• Ganga Orthopedic Research and Education Foundation Senior Research Fellow
  2021 - 2024
• Ganga Orthopedic Research and Education Foundation Project Fellow
  2015 - 2021

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (24)

• Does Cartilage Protein Distribution Vary Across Anatomical Regions of the Femur and Tibia in Osteoarthritic Knees? Insights from Proteomic Analysis.
  Indian journal of orthopaedics 2026 DOI: 10.1007/s43465-026-01774-6
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• When aging becomes degeneration: evidence from metabolomics of healthy age-stratified organ-donor and degenerated lumbar discs
  The Spine Journal 2026 DOI: 10.1016/j.spinee.2026.05.010
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• Do microenvironmental changes in degenerative disc disease reflect in systemic circulation? A proteomic investigation.
  Clinical proteomics 2025 DOI: 10.1186/s12014-025-09563-3
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• Exploring the role of Serpins as a potential molecular target in intervertebral disc degeneration.
  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2025 DOI: 10.1007/s00586-025-09035-0
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• Does the cartilage proteome differ between osteoarthritic knees with varus and valgus deformities? Insights from proteomic analysis.
  Journal of orthopaedics 2025 DOI: 10.1016/j.jor.2025.05.023
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• “Elucidating the immunomodulatory role of endocannabinoids in intervertebral disc degeneration”
  European Spine Journal 2025 DOI: 10.1007/s00586-024-08550-w
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• Identification of extracellular matrix proteins in plasma as a potential biomarker for intervertebral disc degeneration
  European Spine Journal 2024 DOI: 10.1007/s00586-024-08481-6
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• “Does the Gut microbiome influence disc health and disease? –the interplay between dysbiosis, pathobionts, and disc inflammation: A Pilot Study”
  The Spine Journal 2024 DOI: 10.1016/j.spinee.2024.06.020
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• Identification of extracellular matrix proteins in plasma as a potential biomarker in the diagnosis of intervertebral disc degeneration
  2024 DOI: 10.22541/au.170664163.35359466/v1
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• Bacteria in human lumbar discs-subclinical infection or contamination? Metabolomic evidence for colonization, multiplication, and cell-cell cross-talk of bacteria
  SPINE JOURNAL 2023 DOI: 10.1016/J.SPINEE.2022.05.001
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