Sunil Laxman
Institute for Stem Cell Science and Regenerative Medicine, inStem, University of Washington, Anna University, University of Texas Southwestern Medical Center at Dallas
About
My lab is interested in understanding the organizational principles of metabolic regulation, and how the metabolic state of a cell determines cell fate. Areas of research in the lab include understanding (i) organization of metabolic networks, and principles of regulation of cell states, (ii) resource allocation strategies and regulators in cells, and (iii) metabolic exchange, division of labor, and specialization of metabolic functions.
I am an Associate Investigator at the Institute for Stem Cells and Regenerative Medicine (inStem), within the Bangalore Biocluster. Previously, I was a postdoctoral fellow in the Dept. of Biochemistry at UT Southwestern Medical Center, with Drs. Benjamin Tu and Steven McKnight. I completed my Ph.D. with Dr. Joseph Beavo at the University of Washington (Dept. of Pharmacology).
Our research integrates systems-level approaches with detailed molecular mechanisms, and includes mass-spectrometry based metabolite/metabolic flux analysis, genomics and proteomics, genetics, biochemistry, and cell biology. You can read more about our work at http://sunillaxmanlab.weebly.com
Employment
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Institute for Stem Cell Science and Regenerative Medicine Associate Investigator2021 - Present
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inStem Assistant Investigator2014 - 2020
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University of Texas Southwestern Medical Center at Dallas Research Scientist2013 - 2014
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UT Southwestern Medical Center Postdoctoral fellow2007 - 2013
Education
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University of Washington Ph.D.2001 - 2006
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Anna University B. Tech1996 - 2000
Projects & Funding
Projects & funding information is unavailable.
Publications (83)
- The quantitative amino acid economy of yeast reveals public versus private goods and guides syntrophic community design Save
- The yeast mitochondrial porin represses Snf1/AMP kinase signaling to attenuate viral replication Save
- Evolutionary Analysis of Trehalose Breakdown Pathways Save
- A conserved Pho4-Pho84 axis ubiquitously maintains intracellular phosphate homeostasis in yeast Save
- The yeast mitochondrial Porin represses Snf1/AMP Kinase signaling to attenuate viral replication Save
- Altered transposon element-derived genes distort oxygen-free radical scavenger systems in FXD Save
- Lighting up mitochondrial membranes: Reading and writing the physical state of the inner mitochondrial membrane Save
- Quantitative, temporal dynamics of the cellular amino acid economy reveals public vs private goods and enables syntrophic yeast community design Save
- Diurnal variation in skeletal muscle mitochondrial function dictates time‐of‐day‐dependent exercise capacity Save
- Seo1p, a high affinity, plasma membrane transporter of the γ-Glu-met dipeptide in yeasts and fungi Save