Rahul Kumar

About

My current research is focused on hematopoietic stem cell (HSC) and their cancerous counterpart (Leukaemia stem cells (LSC) - CML, AML, and B- ALL). I am trying to identify, validate and target the components of cross-talk between the supporting cells (niche) and HSC/LSC. Specifically, I am keen to decipher the role of metabolism, singling network, immune cells, and extracellular matrix proteins during normal cell functioning and pathology. I have a passion for health care and aspire to utilize the same to aid in the innovation of new medical treatments, products, and/or health discoveries.

Employment

• Georg Speyer Haus Post-doc
  2016 - Present

Education

• Ruprecht Karls Universität Heidelberg Ph.D.
  2011 - 2016
• Indian Institute of Technology Roorkee M.Sc.
  2009 - 2011

Projects & Funding

Projects & funding information is unavailable.

Publications (17)

• The role of the extracellular matrix protein SPOCK2 for bone physiology and hematopoiesis
  Bone 2025 DOI: 10.1016/j.bone.2025.117539
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• Adult skull bone marrow is an expanding and resilient haematopoietic reservoir
  Nature 2024 DOI: 10.1038/s41586-024-08163-9
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• Exploitation of the fibrinolytic system by B-cell acute lymphoblastic leukemia and its therapeutic targeting
  Nature Communications 2024 DOI: 10.1038/s41467-024-54361-4
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• Differential inflammatory conditioning of the bone marrow by acute myeloid leukemia and its impact on progression
  Blood Advances 2024 DOI: 10.1182/bloodadvances.2024012867
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• PDP1 is a key metabolic gatekeeper and modulator of drug resistance in FLT3-ITD-positive acute myeloid leukemia
  Leukemia 2023 DOI: 10.1038/s41375-023-02041-5
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• Impact of mesenchymal stromal cell–derived vesicular cargo on B-cell acute lymphoblastic leukemia progression
  Blood Advances 2023 DOI: 10.1182/bloodadvances.2022007528
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• The differential role of the lipid raft-associated protein flotillin 2 for progression of myeloid leukemia
  Blood Advances 2022 DOI: 10.1182/bloodadvances.2021005992
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• Recent advances in understanding chronic myeloid leukemia: where do we stand?
  Faculty reviews 2021 DOI: 10.12703/r/10-35
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• Chronic Myeloid Leukemia: A Model Disease of the Past, Present and Future
  Cells 2021 DOI: 10.3390/cells10010117
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• The age of the bone marrow microenvironment influences B-cell acute lymphoblastic leukemia progression via CXCR5-CXCL13.
  Blood 2021 DOI: 10.1182/blood.2021011557
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