David Stagg

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Publications (11)

• Ketogenesis mitigates metabolic dysfunction–associated steatotic liver disease through mechanisms that extend beyond fat oxidation
  Journal of Clinical Investigation 2025 DOI: 10.1172/JCI191021
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• Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation
  Science Advances 2025 DOI: 10.1126/sciadv.ads0535
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• Ketogenesis protects against MASLD-MASH progression through mechanisms that extend beyond overall fat oxidation rate
  2024 DOI: 10.1101/2024.10.17.618895
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• Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation
  2024 DOI: 10.1101/2024.07.09.602593
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• Acute aerobic exercise reveals that FAHFAs distinguish the metabolomes of overweight and normal-weight runners
  JCI Insight 2022 DOI: 10.1172/jci.insight.158037
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• Diminished ketone interconversion, hepatic TCA cycle flux, and glucose production in D-β-hydroxybutyrate dehydrogenase hepatocyte-deficient mice
  Molecular Metabolism 2021 DOI: 10.1016/j.molmet.2021.101269
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• Determination of ketone bodies in biological samples via rapid UPLC-MS/MS
  Talanta 2021 DOI: 10.1016/j.talanta.2020.122048
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• Genetic loss of Tmprss6 alters terminal erythroid differentiation in a mouse model of β-thalassemia intermedia.
  Haematologica 2019 DOI: 10.3324/haematol.2018.213371
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• Androgen receptor antagonism drives cytochrome P450 17A1 inhibitor efficacy in prostate cancer.
  The Journal of clinical investigation 2017 DOI: 10.1172/JCI87328
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• Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer.
  Nature chemical biology 2016 DOI: 10.1038/nchembio.2131
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