Manikandan Velayutham

About

I am a biotechnology professional with over five years of experience in research, academia, and preclinical R&D, including roles as Assistant Professor and Research Scholar. My expertise lies in molecular biology, cell culture, and bioassay development, with a focus on bioactive peptides targeting oxidative stress and cancer models. I have hands-on experience in both in vitro and in vivo systems, supporting experimental design and assay standardization. I have authored multiple peer-reviewed publications and actively contribute to collaborative research initiatives. My research interests include drug discovery, translational research, and biopharmaceutical development.

Employment

• G7 Synergon Private Limited CRO Senior exceutive
  2026 - Present
• Saveetha School of Engineering Assistant professor
  2022 - 2026
• SRM Institute of Science and Technology Research Scholar
  2019 - 2022
• National Institute for Interdisciplinary Science and Technology CSIR Trivandrum Kerala IN Project assistant
  2019 - 2019
• Vysya Institute of Management Studies Assistant Professor
  2018 - 2018

Education

• SRM Institute of Science and Technology (Deemed to be University) Ph.D Biotechnology
  2019 - 2022
• Bharathiar University Master of Science in Biotechnology
  2016 - 2018
• Vysya College Bachelar of Science in Biotechnology
  2013 - 2016

Projects & Funding

Projects & funding information is unavailable.

Publications (27)

• DbGTi protein attenuates chromium (VI)-induced oxidative stress via activation of the Nrf2/HO-1 signalling pathway in zebrafish (Danio rerio) larval model
  International Journal of Biological Macromolecules 2024 DOI: 10.1016/j.ijbiomac.2024.136099
  +Save
• DbGTi: Thermostable trypsin inhibitor from Dioscorea bulbifera L. ground tubers: assessment of antioxidant and antibacterial properties and cytotoxicity evaluation using zebrafish model
  International Journal of Biological Macromolecules 2024 DOI: 10.1016/j.ijbiomac.2024.130244
  +Save
• Exploring the neuroprotective potential of KC14 peptide from Cyprinus carpio against oxidative stress-induced neurodegeneration by regulating antioxidant mechanism
  Molecular Biology Reports 2024 DOI: 10.1007/s11033-024-09905-8
  +Save
• Trimetazidine with an adjuvant therapy to normalize the circulating visfatin concentration: Future perspective and mechanistic strategies
  Journal of King Saud University - Science 2023 DOI: 10.1016/j.jksus.2023.102950
  +Save
• Aquatic Peptide: The Potential Anti-Cancer and Anti-Microbial Activity of GE18 Derived from Pathogenic Fungus Aphanomyces invadans
  Molecules 2023 DOI: 10.3390/molecules28186746
  +Save
• Nimbin (N1) and analog N3 from the neem seeds suppress the migration of osteosarcoma MG-63 cells and arrest the cells in a quiescent state mediated via activation of the caspase-modulated apoptotic pathway
  Molecular Biology Reports 2023 DOI: 10.1007/s11033-023-08627-7
  +Save
• Correction to: Serine O-acetyltransferase derived NV14 peptide reduces cytotoxicity in H2O2 induced MDCK cells and inhibits MCF-7 cell proliferation through caspase gene expression
  Molecular Biology Reports 2023 DOI: 10.1007/s11033-023-08383-8
  +Save
• PS9, Derived from an Aquatic Fungus Virulent Protein, Glycosyl Hydrolase, Arrests MCF-7 Proliferation by Regulating Intracellular Reactive Oxygen Species and Apoptotic Pathways
  ACS Omega 2023 DOI: 10.1021/acsomega.3c00336
  +Save
• Syringol, a wildfire residual methoxyphenol causes cytotoxicity and teratogenicity in zebrafish model
  Science of The Total Environment 2023 DOI: 10.1016/j.scitotenv.2022.160968
  +Save
• A synthetic antioxidant molecule, GP13 derived from cysteine desulfurase of spirulina, Arthrospira platensis exhibited anti-diabetic activity on L6 rat skeletal muscle cells through GLUT-4 pathway
  Journal of King Saud University - Science 2023 DOI: 10.1016/j.jksus.2022.102450
  +Save