Sumi S

About

Dr Sumi holds a PhD in biological sciences from the Sree Chitra Tirunal Institute for Medical Sciences & Technology (an institute of National importance), Thiruvananthapuram, and a master’s degree in Biotechnology from the Mahatma Gandhi University, Kottayam, India. She has a broad background in the biomedical sciences, with her PhD degree research focusing on molecular and immunological diagnostic methods in extrapulmonary tuberculosis and her postdoc research on cardiovascular disease biology. Her current research areas are vascular disease biology, haemodynamic alteration and neuroinflammation in disease pathogenesis, epigenetics, etc.

Employment

• Chanakya University Associate Professor
  2025 - Present
• Rajiv Gandhi Centre for Biotechnology Program Scientist
  2009 - 2025

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (25)

• Altered venous flow drives endothelial to mesenchymal transition in varicose veins by suppressing PIEZO1-KLF2 signaling
  Cellular and Molecular Life Sciences 2025 DOI: 10.1007/s00018-025-05854-y
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• Mechanoresponsive ETS1 causes endothelial dysfunction and arterialization in varicose veins via NOTCH4/DLL4 signaling
  European Journal of Cell Biology 2024 DOI: 10.1016/j.ejcb.2024.151420
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• Oscillatory shear stress modulates Notch-mediated endothelial mesenchymal plasticity in cerebral arteriovenous malformations
  Cellular & Molecular Biology Letters 2023 DOI: 10.1186/s11658-023-00436-x
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• Molecular Biomarkers and Drug Targets in Brain Arteriovenous and Cavernous Malformations: Where Are We?
  Stroke 2022 DOI: 10.1161/STROKEAHA.121.035654
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• Genetic and Epigenetic Regulation by Gut Microbe-Modulated Metabolites in Chronic Metabolic Diseases
  Human Microbiome 2022 DOI: 10.1007/978-981-16-7672-7_5
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• Aberrant regulation of retinoic acid signaling genes in cerebral arterio venous malformation nidus and neighboring astrocytes
  Jaya Mary Thomas, Dhakshmi Sasankan, Sumi Surendran +3 more
  Journal of Neuroinflammation 2021 DOI: 10.1186/s12974-021-02094-2
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• Shear Stress Alterations Activate BMP4/pSMAD5 Signaling and Induce Endothelial Mesenchymal Transition in Varicose Veins
  Karthika Chandran Latha, Ahalya Sreekumar, Vyshna Beena +7 more
  Cells 2021 DOI: 10.3390/cells10123563
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• Neurovascular inflammation in the pathogenesis of brain arteriovenous malformations
  Journal of Cellular Physiology 2021 DOI: 10.1002/jcp.30226
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• Heat shock proteins-driven stress granule dynamics: yet another avenue for cell survival
  Akanksha Verma, S. Sumi, Mahendra Seervi
  Apoptosis 2021 DOI: 10.1007/s10495-021-01678-w
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• Hemodynamics mediated epigenetic regulators in the pathogenesis of vascular diseases
  C. L. Karthika, S. Ahalya, N. Radhakrishnan +2 more
  Molecular and Cellular Biochemistry 2021 DOI: 10.1007/s11010-020-03890-9
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• Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathway
  Mahendra Seervi, S. Sumi, Aneesh Chandrasekharan

  +2 more

  • Abhay Kumar Sharma
  • Thankayyan Retnabai Santhoshkumar
  Cellular Oncology 2019 DOI: 10.1007/s13402-019-00451-1
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• Vein Size and Disease Severity in Chronic Venous Diseases
  N. Radhakrishnan, Deepu George, R. Jayakrishnan +2 more
  International Journal of Angiology 2018 DOI: 10.1055/s-0038-1639355
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• Gene expression analysis of nidus of cerebral arteriovenous malformations reveals vascular structures with deficient differentiation and maturation
  Jaya Mary Thomas, Sumi Surendran, Mathew Abraham +4 more
  PLOS ONE 2018 DOI: 10.1371/journal.pone.0198617
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• ENPP1 121Q functional variant enhances susceptibility to coronary artery disease in South Indian patients with type 2 diabetes mellitus
  S. Sumi, Surya Ramachandran, V. Ramankutty +4 more
  Molecular and Cellular Biochemistry 2017 DOI: 10.1007/s11010-017-3057-2
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• Role of Non-coding RNAs in Vascular Complications of Diabetes Mellitus
  Mechanisms of Vascular Defects in Diabetes Mellitus 2017 DOI: 10.1007/978-3-319-60324-7_15
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• Genetic and epigenetic mechanisms in the development of arteriovenous malformations in the brain
  Jaya Mary Thomas, Sumi Surendran, Mathew Abraham +2 more
  Clinical Epigenetics 2016 DOI: 10.1186/s13148-016-0248-8
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• Arterialization and anomalous vein wall remodeling in varicose veins is associated with upregulated FoxC2-Dll4 pathway
  Sumi Surendran, Kalpana S. Ramegowda, Aarcha Suresh +5 more
  Laboratory Investigation 2016 DOI: 10.1038/labinvest.2015.167
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• PPIA rs6850: A > G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease
  A. Vinitha, Vellappillil Raman Kutty, Asokachandran Vivekanand +8 more
  Molecular and Cellular Biochemistry 2016 DOI: 10.1007/s11010-015-2632-7
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• Dot-Immunobinding Assay (Dot-Iba)
  Sumi Surendran, Annamma Mathai, Vishnampet Venkataraman Radhakrishnan
  Methods in Molecular Biology 2015 DOI: 10.1007/978-1-4939-2694-7_14
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• Forkhead box C2 Promoter Variant c.-512C>T Is Associated with Increased Susceptibility to Chronic Venous Diseases
  Sumi Surendran, Athira Girijamma, Radhakrishnan Nair +6 more
  PLoS ONE 2014 DOI: 10.1371/journal.pone.0090682
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