YW
Yue Wang
A*star Infectious Disease Labs, National University of Singapore, University of Minnesota, Institute of Molecular and Cell Biology
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Fungal and yeast genetics research · Antifungal resistance and susceptibility · Genomics and Phylogenetic Studies
0000-0002-1211-2822
Employment
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A*star Infectious Disease Labs Senior Principal Investigator2022 - Present
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National University of Singapore Adjunct Professor2013 - Present
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Institute of Molecular and Cell Biology Research Director2009 - 2022
- 2006 - 2008
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National University of Singapore Adjunct Associate Professor2000 - 2012
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Institute of Molecular and Cell Biology Principal Investigator1993 - 2008
Education
- 1982 - 1988
Projects & Funding
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Unraveling Candida albicans’ mechanisms for balancing growth forms and rate to sustain virulence through metabolic adaptation National Medical Research Council2024 - 2027
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Integrated genomics and molecular genetics approach to understand antifungal resistance mechanisms among invasive Candida pathogens and to improve patient care TRIDENT Programme2024 - 2026
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Elucidation of the mechanism of action of the global stress regulator, DINOR, in the super fungus Candida auris National Medical Research Council2022 - 2025
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Mapping the signaling pathways coupling mitochondrial functions with the invasive hyphal growth in the fungal pathogen Candida albicans National Medical Research Council2021 - 2023
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Elucidation of antifungal resistance mechanisms in the emergent fungal pathogen Candida auris Agency for Science, Technology and Research2021 - 2023
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Endogenous signals regulating hyphal development in the principal fungal pathogen Candida albicans National Research Foundation Singapore2020 - 2023
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Identification and elucidation of antifungal resistance mechanisms in the human fungal pathogen Candida albicans National Medical Research Council2018 - 2021
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Anti-PG immunotherapy for rheumatoid arthritis A*STAR-BMRC2016 - 2017
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Managing gut microbiota and the use of ß-lactam antibiotics as novel strategies combating invasive Candida albicans infection National Medical Research Council2016 - 2019
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Novel predictive biomarkers and therapeutic strategies for nosocomial candidemia National Medical Research Council2012 - 2016
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Commercialization of Technology Grant Agency for Science, Technology and Research2001 - 2002
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Anti-fungal coating to reduce medical-device associated Candida infection Agency for Science, Technology and Research
Publications (129)
- Direct RNA sequencing and signal alignment reveal RNA structure ensembles in a eukaryotic cell Save
- A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins Save
- Boronic acid derivatives inhibit Candida albicans growth by compromising energy metabolism Save
- Candida auris vacuolar calcium pump mediates fluconazole efflux and resistance evolution Save
- Macrophage-membrane-camouflaged nanoagents for precise bacterial clearance Save
- Nanozymes: An emerging arsenal for the treatment of Candida albicans infection Save
- Synthetic High‐Throughput Microarrays of Peptidoglycan Fragments as a Novel Sero‐Diagnostic Tool for Patient Antibody Profiling Save
- The impact of the host microbiota on Candida albicans infection Save
- Nanorobots to Treat Candida albicans Infection Save
- Pathogenic fungi: Novel targets and theranostic strategies Save
- Genome‐wide profiling of piggyBac transposon insertion mutants reveals loss of the F1F0 ATPase complex causes fluconazole resistance in Candida glabrata Save
- Cytochrome c regulates hyphal morphogenesis by interfering with cAMP-PKA signaling in Candida albicans Save
- The transcription factor Rpn4 activates its own transcription and induces efflux pump expression to confer fluconazole resistance in Candida auris Save
- Water-Mediated In Situ Fabrication of CuI Nanoparticles on Flexible Cotton Fabrics as a Sustainable and Skin-Compatible Coating with Broad-Spectrum Antimicrobial Efficacy Save
- Impact of the host microbiota on fungal infections: New possibilities for intervention? Save
- Escherichia coli has robust regulatory mechanisms against elevated peptidoglycan cleavage by lytic transglycosylases Save
- Comprehensive Interactome Analysis for the Sole Adenylyl Cyclase Cyr1 of Candida albicans Save
- From Jekyll to Hyde: The Yeast–Hyphal Transition of Candida albicans Save
- Inactivating the mannose-ethanolamine phosphotransferase Gpi7 confers caspofungin resistance in the human fungal pathogen Candida albicans Save
- Author Correction: A peptidoglycan storm caused by β-lactam antibiotic’s action on host microbiota drives Candida albicans infection Save