JW
Jim Warwicker
University of Manchester
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Protein Structure and Dynamics · Enzyme Structure and Function · Protein purification and stability
0000-0002-1302-0815
Employment
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (142)
- Prediction of pH-sensing histidine residues in human cells Save
- Charged amino acid propensities and solubility: lysine is elevated at the termini of helices in E. coli proteins Save
- Dioxygen Activation by Caenorhabditis elegans Ferritin: The Effect of the Second‐Coordination Sphere on O2 Reduction to H2O2 Save
- Computation suggests that the cell adhesion sub-proteome is enriched for sites of pH-dependence and charge burial Save
- Outward-facing P-glycoprotein bound to drug displays nucleotide-dependent drug egress mechanism Save
- Drug-bound P-glycoprotein reveals nucleotide-dependent ligand pockets and ingress channels Save
- Computational investigation suggests that the cell adhesion sub-proteome is enriched for sites of pH-dependence and charge burial, whilst some key intracellular pathways may be shielded from pH fluctuations Save
- Nucleotide Asymmetry and Flexible Linker Dynamics Modulate Drug Efflux Cycle of P-glycoprotein, a Computational Study Save
- Methylene Group Insertion into a C−N Bond. The Mechanism for the Biosynthesis of Dehydrofosmidomycin by a Nonheme Iron Oxygenase. Save
- Nucleotide asymmetry and flexible linker dynamics modulate drug efflux cycle of P-glycoprotein, A computational study Save
- What is the Origin of the Regioselective C3‐Hydroxylation of L‐Arg by the Nonheme Iron Enzyme Capreomycin C? Save
- Computational investigation of missense somatic mutations in cancer and potential links to pH-dependence and proteostasis Save
- Computational investigation of missense somatic mutations in cancer and potential links to pH-dependence and proteostasis Save
- How Does the Nonheme Iron Enzyme NapI React Through L-Arginine Desaturation Rather Than Hydroxylation? A QM/MM Study. Save
- Computational investigation of mechanisms for pH modulation of human chloride channels Save
- How is substrate halogenation triggered by the vanadium haloperoxidase from Curvularia inaequalis? Save
- Chemometrics in Protein Formulation: Stability Governed by Repulsion and Protein Unfolding Save
- A pH-dependent cluster of charges in a conserved cryptic pocket on flaviviral envelopes Save
- ATP6V0C variants impair V-ATPase function causing a neurodevelopmental disorder often associated with epilepsy Save
- Investigating the Orientation of an Interfacially Adsorbed Monoclonal Antibody and Its Fragments Using Neutron Reflection Save