Swetha Mundanattu

About

Researcher with 9 years of experience in molecular biology. Expertise in cell culture, animal handling, bioprospecting, chemoprevention, chemosensitization, mitochondrial biology, aging, and injury models.

Employment

• Augusta University Post doctoral fellow
  2024 - Present
• Sree Chitra Thirunal Institute for Medical Sciences and Technology Post doctoral fellow
  2023 - 2024
• Rajiv Gandhi Centre for Biotechnology ICMR Senior Research Fellow
  2023 - 2023
• Rajiv Gandhi Centre for Biotechnology PhD scholar
  2017 - 2023

Education

• Rajiv Gandhi Centre for Biotechnology PhD scholar

Projects & Funding

Projects & funding information is unavailable.

Publications (22)

• Orphan drug uttroside B impedes MASH progression and HCC development in experimental models
  JHEP Reports 2026 DOI: 10.1016/j.jhepr.2025.101626
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• Uttroside B, a US FDA-designated ‘Orphan Drug’, mitigates the development of hepatocellular carcinoma and its pulmonary metastasis via EGFR/ERK-mediated inhibition of SREBP-1 and STAT-3
  Cell Death Discovery 2026 DOI: 10.1038/s41420-026-03055-5
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• Differential expression of senescence markers p16, p21 and p21 transcript variants in oxidative stress mediated cellular senescence
  Free Radical Biology and Medicine 2025 DOI: 10.1016/j.freeradbiomed.2025.10.164
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• Inhibition of pyruvate dehydrogenase kinase protects cells from SASP-induced secondary senescence.
  Free Radical Biology and Medicine 2025 DOI: 10.1016/j.freeradbiomed.2025.10.161
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• Intranasal administration of plasma-extracellular vesicle-derived microRNA improves cognitive function in a mouse model of familial Alzheimer’s disease
  Free Radical Biology and Medicine 2025 DOI: 10.1016/j.freeradbiomed.2025.10.243
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• Systemic Administration of Mitochondria Improves Organ Function and Survival in a Mouse Model of Hemorrhagic Shock Injury
  Free Radical Biology and Medicine 2025 DOI: 10.1016/j.freeradbiomed.2025.10.063
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• Evaluating the therapeutic efficacy of the US FDA-designated ‘Orphan drug’, uttroside B in impeding hepatocarcinogenesis via induction of immunogenic apoptosis, using a murine model of Aflatoxin B1-induced liver carcinogenesis
  2025 DOI: 10.1101/2025.09.08.674785
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• Mitochondria-targeted therapy with metformin and MitoQ reduces oxidative stress, improves mitochondrial function, and restores metabolic homeostasis in a murine model of Gulf War Illness
  Redox Biology 2025 DOI: 10.1016/j.redox.2025.103714
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• Bach1 deficiency promotes expression of p21 transcript variants in murine embryonic fibroblasts
  Free Radical Biology and Medicine 2024 DOI: 10.1016/j.freeradbiomed.2024.10.204
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• Role of plant-derived extracellular nanovesicles in triggering innate immune response against plant pathogens
  Nanotechnology in Plant Health 2024
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