Conor Barry

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Publications (8)

• Efficacy, Tolerability, and Pharmacokinetic Studies of Antibody-Drug Conjugates Containing a Low-Potency Pyrrolobenzodiazepine Dimer.
  Molecular cancer therapeutics 2022 DOI: 10.1158/1535-7163.mct-22-0145
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• Simultaneous monitoring of multiple attributes of pyrrolobenzodiazepine antibody-drug conjugates by size exclusion chromatography - high resolution mass spectrometry.
  Journal of pharmaceutical and biomedical analysis 2021 DOI: 10.1016/j.jpba.2021.114287
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• Improved Physical Stability of an Antibody-Drug Conjugate Using Host-Guest Chemistry.
  Bioconjugate chemistry 2019 DOI: 10.1021/acs.bioconjchem.9b00809
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• TR1801-ADC: a highly potent cMet antibody-drug conjugate with high activity in patient-derived xenograft models of solid tumors.
  Molecular oncology 2019 DOI: 10.1002/1878-0261.12600
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• Synthesis and evaluation of pyrrolobenzodiazepine dimer antibody-drug conjugates with dual β-glucuronide and dipeptide triggers.
  European journal of medicinal chemistry 2019 DOI: 10.1016/j.ejmech.2019.06.044
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• A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.
  PLoS neglected tropical diseases 2019 DOI: 10.1371/journal.pntd.0007373
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• ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies.
  Molecular cancer therapeutics 2016 DOI: 10.1158/1535-7163.mct-16-0233
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• The three Mycobacterium tuberculosis antigen 85 isoforms have unique substrates and activities determined by non-active site regions.
  The Journal of biological chemistry 2014 DOI: 10.1074/jbc.m114.581579
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