JYOTSNA AMBURE

Employment

• MultiTargetAI JPS LLP Senior Scientist
  2023 - Present
• MolDrug AI Systems S L Senior Researcher (MSCA-IF Fellow)
  2021 - Present
• University of Gdańsk Visiting Research Fellow
  2017 - 2017
• Bombay College of Pharmacy Junior Research Fellow
  2012 - 2012

Education

• Bose Institute PhD
  2013 - 2019
• National Institute of Pharmaceutical Education and Research Master
  2010 - 2012
• Institute of Chemical Technology Bachelor
  2006 - 2010

Projects & Funding

Projects & funding information is unavailable.

Publications (17)

• G4-QuadScreen: A Computational Tool for Identifying Multi-Target-Directed Anticancer Leads against G-Quadruplex DNA
  Cancers 2023 DOI: 10.3390/cancers15153817
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• Prion-derived tetrapeptide stabilizes thermolabile insulin via conformational trapping
  iScience 2021 DOI: 10.1016/j.isci.2021.102573
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• Andrographolide binds to ATP-binding pocket of VEGFR2 to impede VEGFA-mediated tumor-angiogenesis
  Scientific Reports 2019 DOI: 10.1038/s41598-019-40626-2
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• Identifying natural compounds as multi-target-directed ligands against Alzheimer’s disease: an in silico approach
  Journal of Biomolecular Structure and Dynamics 2019 DOI: 10.1080/07391102.2018.1456975
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• In Silico Screening and Binding Characterization of Small Molecules toward a G-Quadruplex Structure Formed in the Promoter Region of c-MYC Oncogene
  ACS Omega 2017 DOI: 10.1021/acsomega.6b00531
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• LINCRNA00273 promotes cancer metastasis and its G-Quadruplex promoter can serve as a novel target to inhibit cancer invasiveness
  Oncotarget 2017 DOI: 10.18632/oncotarget.22622
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• Mephebrindole, a synthetic indole analog coordinates the crosstalk between p38MAPK and eIF2α/ATF4/CHOP signalling pathways for induction of apoptosis in human breast carcinoma cells
  Apoptosis 2016 DOI: 10.1007/s10495-016-1268-8
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• Skeleton selectivity in complexation of chelerythrine and chelerythrine-like natural plant alkaloids with the G-quadruplex formed at the promoter of: C-MYC oncogene: In silico exploration
  RSC Advances 2016 DOI: 10.1039/c6ra04671a
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• G-actin guides p53 nuclear transport: Potential contribution of monomeric actin in altered localization of mutant p53
  Scientific Reports 2016 DOI: 10.1038/srep32626
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• Discovery and Structural Characterization of G-quadruplex DNA in Human Acetyl-CoA Carboxylase Gene Promoters: Its Role in Transcriptional Regulation and as a Therapeutic Target for Human Disease
  Journal of Medicinal Chemistry 2016 DOI: 10.1021/acs.jmedchem.6b00453
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