Bharathwaj Sathyamoorthy

About

Dr. Bharathwaj Sathyamoorthy received his B.Sc. from University of Madras (2005, Ramakrishna Mission Vivekananda College) and M.Sc. from Indian Institute of Technology Madras (2007) in Chemistry. He pursued his Ph.D. under the guidance of Prof. Thomas Szyperski (State University of New York at Buffalo, 2013) in development and application of solution-state NMR spectroscopic techniques towards biomolecular characterization. He continued his postdoctoral research with Prof. Hashim M. Al-Hashim (University of Michigan followed by Duke University) in understanding nucleic acids structure and dynamics. He started his independent research at Indian Institute of Science Education and Research Bhopal (IISERB) from 2015 and is focusing on developing novel NMR methods towards characterizing structure of DNA with non-canonical nucleotides and non-duplex topologies.

Employment

• Indian Institute of Science Education and Research Bhopal Associate Professor
  2023 - Present
• Indian Institute of Science Education and Research Bhopal Assistant Professor
  2015 - 2023

Education

• University at Buffalo - The State University of New York Ph.D.
  2007 - 2013
• Indian Institute of Technology Madras M.Sc.
  2005 - 2007
• Ramakrishna Mission Vivekananda College, University of Madras B.Sc.
  2002 - 2005

Projects & Funding

Projects & funding information is unavailable.

Publications (30)

• NMR-based conformational analysis of DNA G-quadruplex guides mapping essential structure–function relationship in protein chaperoning
  Physical Chemistry Chemical Physics 2026 DOI: 10.1039/D5CP03909F
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• Unfolding of i-Motif DNA Structures Using G-Quadruplex Stabilizing Bisindolylmaleimide Ligands
  The Journal of Physical Chemistry B 2025 DOI: 10.1021/acs.jpcb.5c06412
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• Loop Nucleotide Chemical Shifts as a Tool to Characterize DNA G‐Quadruplexes
  ChemPhysChem 2025 DOI: 10.1002/cphc.202401075
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• Ribose Sugar Alters Conformational Sampling of G⋅T Mismatched Duplex DNA
  Chemistry – An Asian Journal 2025 DOI: 10.1002/asia.202401335
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• Conformational Plasticity of Parallel G-Quadruplex─Implications on Duplex–Quadruplex Motifs
  Journal of the American Chemical Society 2023 DOI: 10.1021/jacs.3c03218
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• 5-Formylcytosine weakens the G–C pair and imparts local conformational fluctuations to DNA duplexes
  Physical Chemistry Chemical Physics 2023 DOI: 10.1039/D2CP04837J
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• Bisindolylmaleimide Ligands Stabilize c-MYC G-Quadruplex DNA Structure and Downregulate Gene Expression
  Biochemistry 2022 DOI: 10.1021/acs.biochem.2c00116
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• Characterization of DNA G-quadruplex Topologies with NMR Chemical Shifts
  The Journal of Physical Chemistry Letters 2020 DOI: 10.1021/acs.jpclett.0c02969
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• A metabolomics footprint approach to understanding the benefits of synbiotics in functional foods and dietary therapeutics for health, communicable and non-communicable diseases
  Food Research International 2020 DOI: 10.1016/j.foodres.2019.108679
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• Characterizing Watson-Crick versus Hoogsteen Base Pairing in a DNA-Protein Complex Using Nuclear Magnetic Resonance and Site-Specifically 13 C- and 15 N-Labeled DNA
  Biochemistry 2019 DOI: 10.1021/acs.biochem.9b00027
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