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Nizar Al-Shar'i
Jordan University of Science and Technology, Al-Ghad International Colleges for Health Sciences, University of Strathclyde
Research areas: Chemistry · Organic Chemistry · Computational Drug Discovery Methods · Synthesis and Characterization of Heterocyclic Compounds · Synthesis and biological activity
0000-0002-1599-5704
Employment
- 2023 - Present
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Jordan University of Science and Technology Department head2014 - 2018
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Jordan University of Science and Technology Assistant Dean of Pharmacy for Postgraduate Students Affairs and Quality Control2013 - 2014
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Al-Ghad International Colleges for Health Sciences Department head2007 - 2009
Education
- 2009 - 2013
- 2003 - 2007
- 1996 - 2001
Projects & Funding
Projects & funding information is unavailable.
Publications (30)
- CHK1 kinase inhibition: identification of allosteric hits using MD simulations, pharmacophore modeling, docking and MM-PBSA calculations Save
- Anti-tubercular activity and molecular docking studies of indolizine derivatives targeting mycobacterial InhA enzyme Save
- In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies of substituted 1,2,4-oxadiazole analogues against Mycobacterium tuberculosis Save
- Tuberculosis: An Update on Pathophysiology, Molecular Mechanisms of Drug Resistance, Newer Anti-TB Drugs, Treatment Regimens and Host-Di-rected Therapies Save
- Design, synthesis and biological evaluation of novel glyoxalase I inhibitors possessing diazenylbenzenesulfonamide moiety as potential anticancer agents Save
- Tackling COVID-19: identification of potential main protease inhibitors via structural analysis, virtual screening, molecular docking and MM-PBSA calculations Save
- Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking Save
- Discovery of a nanomolar glyoxalase-I inhibitor using integrated ligand-based pharmacophore modeling and molecular docking Save
- Discovery of novel glyoxalase-I inhibitors using computational fragment-based drug design approach Save
- Identification of CHK1 Kinase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking Save
- Amino-carboxamide benzothiazoles as potential LSD1 hit inhibitors. Part I: Computational fragment-based drug design Save
- Discovery of a nanomolar inhibitor of the human glyoxalase-I enzyme using structure-based poly-pharmacophore modelling and molecular docking Save
- Molecular Dynamics Simulations of Adenosine Receptors: Advances, Applications and Trends Save
- Hit identification of SMYD3 enzyme inhibitors using structure-based pharmacophore modeling Save
- Recent Advances in Glyoxalase-I Inhibition Save
- Design, synthesis and biological evaluation of potential novel zinc binders targeting human glyoxalase-i; a validated target for cancer treatment Save
- Computational and experimental exploration of the structure–activity relationships of flavonoids as potent glyoxalase-I inhibitors Save
- Experimental and Computational Comparative Study of The Supercritical Fluid Technology (SFT) and Kneading Method in Preparing β-Cyclodextrin Complexes with Two Essential Oils (Linalool and Carvacrol) Save
- Novel Thiazole Carboxylic Acid Derivatives Possessing a “Zinc Binding Feature” as Potential Human Glyoxalase-I Inhibitors Save
- Peptide consensus sequence determination for the enhancement of the antimicrobial activity and selectivity of antimicrobial peptides Save