0000-0002-1838-9718 About
My research centers on identifying and developing novel antimicrobial agents against resistant pathogens. In our lab, we characterized a furanone derivative with potent antifungal and immunomodulatory effects, showing its ability to rescue disseminated cryptococcosis in mouse models. This work highlights the compound’s dual action direct fungal inhibition and immune enhancement offering a promising therapeutic strategy for severe by Candida spp.. I am currently advancing this candidate through pharmacokinetic studies and nanoformulation development to pave the way for clinical translation.
Research Focus Areas:
1. Actinomycetes bioprospecting
2. Antifungals and resistance modulators discovery
3. Genomic surveillance
4. Biofilm inhibition strategies
5. Clean-room biocontamination control
Associate Editor @ AMB Express, Since 2024
Employment
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SASTRA University Professor, Associate Dean- Student Welfare2024 - Present
Education
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SASTRA University PhD
Projects & Funding
Projects & funding information is unavailable.
Publications (29)
- Virulence and pathogenicity of secondary fungal infections Save
- Elucidating the effect of cations in environmental-clinical interface of Klebsiella biofilm and related genes Save
- Hybrid genome sequence of Cryptococcus neoformans of Indian origin and comparative genome analysis Save
- Exploration of novel β-lactamase inhibitors against Klebsiella pneumoniae using fragment-based drug discovery approach Save
- Characterization and applications of MSS pigment isolated from Streptomyces ardesiacus Save
- Elucidation of furanone as ergosterol pathway inhibitor in Cryptococcus neoformans Save
- Complete genome sequence, phenotypic correlation and pangenome analysis of uropathogenic Klebsiella spp Save
- Comprehensive screening of marine metabolites against class B1 metallo-β-lactamases of Klebsiella pneumoniae using two-pronged in silico approach Save
- In vitro and in silico screening of Klebsiella pneumoniae new Delhi metallo-β-lactamase-1 inhibitors from endophytic Streptomyces spp. Save
- Biofilm of Klebsiella pneumoniae minimize phagocytosis and cytokine expression by macrophage cell line Save