Matthew Fisher
Imperial College London, University of Edinburgh
Research areas: Agricultural and Biological Sciences · Ecology, Evolution, Behavior and Systematics · Amphibian and Reptile Biology · Fungal Infections and Studies · Antifungal resistance and susceptibility
About
Prof Matthew Fisher is a biologist with a focus on the biodiversity and evolutionary ecology of pathogenic fungi. He heads the Fungal Pathogens Research Group in the Department of Infectious Disease Epidemiology and leads the Fungal Pathogens theme in the MRC Centre for Global Infectious Disease Analysis. His research uses evolutionary genomics, molecular taxonomy, field ecology and experimentation to investigate the biological and environmental factors that are driving emerging fungal diseases across managed and natural ecosystems. His lab works across scales ranging from single-hosts through to whole-earth studies; he has maintained a continual presence at ecological study sites for over 15 years where he studies the impact of environmental change on host/pathogen dynamics and and uses fieldwork sites across Africa, Madagascar, Europe and Asia. His research investigates complex cross-Kingdom interactions using big-data approaches and draws on world-wide collaborations and datasets that he has nurtured over 20 years of ecological research. His ultimate research goal is focused on developing novel genomic, epidemiological and experimental methods to understand the complex interactions leading to upswings of new fungal infections in new places and their ensuing impact on ecosystem health. Professor Fishers laboratory is supported by a diverse array of funders including the Wellcome Trust, NERC, BBSRC, MRC, the Leverhulme Trust and BioDiversa.
Employment
Education
- 1994 - 1997
Projects & Funding
-
Understanding and mitigating the impact of emerging antifungal resistance Wellcome Trust2020 - 2024
-
Understanding links between microbial communities and emerging fungal pathogens in complex ecosystem Natural Environment Research Council2018 - 2021
-
The evolutionary dynamics of multiazole resistance in pathogenic Aspergillus fungi Natural Environment Research Council2016 - 2019
-
The spatial epidemiology and molecular evolution of panzootic amphibian chytridiomycosis Natural Environment Research Council2013 - 2017
-
An evolutionary population genomics approach to determine the genetic basis of virulence in the pathogenic fungus Cryptococcus neoformans Medical Research Council2012 - 2015
-
Quantifying the population-level cost of amphibian chytridiomycosis in a changing montane ecosystem Natural Environment Research Council2010 - 2014
-
RACE: Risk Assessment of Chytridiomycosis to European amphibian biodiversity Natural Environment Research Council2009 - 2013
-
Comparative and functional genomic analysis of pathogenicity in Penicillium marneffei. Wellcome Trust2009 - 2012
-
Relationship between environmental, ecological and genetic drivers of emergence in amphibian chytridiomycosis. Natural Environment Research Council2007 - 2010
-
Relationship between environmental, ecological and genetic drivers of emergence in amphibian chytridiomycosis. Natural Environment Research Council2007 - 2011
-
The Xenopus tropicalis response to infection by Batrachochytrium dendrobatidis Biotechnology and Biological Sciences Research Council2007 - 2008
-
The population genetics and biology of emerging opportunistic pathogens. Wellcome Trust2003 - 2005
-
The population genetics and biology of emerging opportunistic pathogens. Wellcome Trust2002 - 2005
Publications (225)
- Environmental Terbinafine Contamination and Dermatophyte Resistance: A One Health Hypothesis in Need of Ecological Validation Save
- A Direct DNA Extraction Workflow for Metabarcoding Fungal Bioaerosols From Adhesive Samplers Save
- The pangenome of Aspergillus fumigatus highlights the dynamics of gene gain-loss over evolutionary timescales in a human fungal pathogen Save
- Rapid Emergence of an Amphibian Pathogen Coincided With Historic Amphibian Declines in the Neotropics Save
- Metabolic control of mitochondrial plasticity and extracellular vesicle biology drives Cryptococcus neoformans virulence Save
- Unraveling the disease pyramid: the role of environmental micro-eukaryotes in amphibian resistance to the deadly fungal pathogen Batrachochytrium dendrobatidis Save
- A Direct DNA Extraction Workflow for Metabarcoding Fungal Bioaerosols from Adhesive Samplers Save
- Rapid emergence of Trichophyton indotineae (Trichophyton mentagrophytes ITS genotype VIII) observed in the United Kingdom, up to August 2025 Save
- Recent European origin of azole resistance in the critical priority fungal pathogen Aspergillus fumigatus Save
- Genomic and phenotypic insights into the expanding phylogenetic landscape of the Cryptococcus genus Save
- Appearance of Environment‐Linked Azole Resistance in the Aspergillus fumigatus Complex in New Zealand Save
- Genomic epidemiology links azole-resistant Aspergillus fumigatus hospital bioaerosols to chronic respiratory aspergillosis Save
- Origins of the ‘vampire fungus’ that causes white-nose syndrome in bats Save
- Genomic and phenotypic insights into the expanding phylogenetic landscape of the Cryptococcus genus Save
- Fungal impacts on Earth’s ecosystems Save
- West London Healthy Home and Environment (WellHome) Study: Protocol for a Community-Based Study Investigating Exposures Across the Indoor-Outdoor Air Pollution Continuum in Urban Communities Save
- Elevated mutation rates in multi-azole resistant Aspergillus fumigatus drive rapid evolution of antifungal resistance Save
- The Impact of the Fungal Priority Pathogens List on Medical Mycology: A Northern European Perspective Save
- Revealing the genome of the microsporidian Vairimorpha bombi, a potential driver of bumble bee declines in North America Save
- Elevated mutation rates in the multi-azole resistantAspergillus fumigatusclade drives rapid evolution of antifungal resistance Save