Abhisek Jana
Indian Institute of Technology Bombay, CSIR CGCRI, National Institute of Technology Durgapur, Jadavpur University, Ramakrishna Mission Vivekananda Centenary College, Rahara
0000-0002-1967-1387
About
Dr. Abhisek Jana is a computational and medicinal chemist specializing in epigenetics, drug discovery, and bioinformatics. He completed his Ph.D. in Chemistry at the National Institute of Technology, Durgapur, India. His doctoral research focused on computational investigations of lysine methyltransferase G9a and identifying potential epigenetic inhibitors. Dr. Jana has extensive expertise in computational tools, including molecular dynamics simulations (AMBER, GROMACS), molecular docking, and pharmacophore modeling software. His work has contributed to the identification and optimization of small-molecule inhibitors targeting epigenetic enzymes and other therapeutic targets. He has authored several high-impact publications in internationally reputed journals. Beyond his computational techniques, Dr. Jana has hands-on experience in organic synthesis, bioassay techniques, and the use of advanced spectroscopic instruments. He has received numerous accolades, including the prestigious CSIR UGC NET-JRF, Lecturership and the INSPIRE Scholarship. Dr. Jana is also an enthusiastic mentor, having guided several Master students who advanced to doctoral programs at premier institutes in India. Currently serving as an Institute Postdoctoral Fellow at IIT Bombay, he continues to explore innovative approaches in chemical biology.
Employment
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Indian Institute of Technology Bombay Post Doctoral Felllow2024 - Present
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CSIR CGCRI Project Associate2018 - 2019
Education
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National Institute of Technology Durgapur Ph.D2019 - 2024
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Jadavpur University M.Sc2015 - 2017
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Ramakrishna Mission Vivekananda Centenary College, Rahara B.Sc2012 - 2015
Projects & Funding
Projects & funding information is unavailable.
Publications (10)
- Structure-Based Virtual Screening, In Vitro and In Silico Analysis Identified Novel Potent m6A Demethylase FTO Inhibitors as Promising Neurotherapeutic Agents Save
- Uncovering New Hits against Lysine Demethylase (LSD1) using Dual 3D Pharmacophores and Multi-Tier Rational Screening Save
- Targeting human arginyltransferase and post-translational protein arginylation: a pharmacophore-based multilayer screening and molecular dynamics approach to discover novel inhibitors with therapeutic promise Save
- G9a an Epigenetic Therapeutic Strategy for Neurodegenerative Conditions: From Target Discovery to Clinical Trials Save
- Integration of ligand and structure-based pharmacophore screening for the identification of novel natural leads against Euchromatic histone lysine methyltransferase 2 (EHMT2/G9a) Save
- Repurposing of Raltitrexed as an Effective G9a/EHMT2 Inhibitor and Promising Anti-Alzheimer’s Agent Save
- 3D QSAR pharmacophore based lead identification of G9a lysine methyltransferase towards epigenetic therapeutics Save
- Computational Investigation on Natural Quinazoline Alkaloids as Potential Inhibitors of the Main Protease (Mpro) of SARS-CoV-2 Save
- Computational investigation on natural quinazoline alkaloids as potential inhibitors of the main protease (Mpro) of SARS_CoV_2 Save
- Characterization of the binding of strychnine with bovine β-lactoglobulin and human lysozyme using spectroscopic, kinetic and molecular docking analysis Save