Eugene Osae
Also known as: A.E. Osae, E.A. Osae, Eugene Appenteng Osae
Kwame Nkrumah University of Science and Technology, Kumasi.
About
I hold a Doctor of Optometry (OD) degree from the Kwame Nkrumah University of Science and Technology, Ghana and I am currently a Ph.D. candidate and clinical research assistant at the University of Houston, College of Optometry, in Houston , Texas, USA. My research focuses on metabolic syndrome and its effects on the Meibomian gland and the ocular surface. Metabolic syndrome is a cluster of conditions including obesity, dyslipidemia, hypertension, systemic inflammation, and hyperglycemia. Metabolic syndrome is on the rise and the obesity which is a global epidemic is a major risk factor for type II diabetes. Metabolic syndrome has other complications on the eye.
Maintaining a healthy ocular surface is challenging, even in healthy individuals and this becomes far more challenging in inflammatory states such as metabolic syndrome. Using a diet-induced obesity model, where mice develop metabolic syndrome I employ a multiprong approach of meibography, electron microscopy and lipidomics to investigate the structural and functional alterations in the meibomian gland and general ocular surface homeostasis. The goal is to gain a better understanding of how ocular surface health is challenged by inflammatory diseases (obesity, diabetes, autoimmunity and dry eye) and how a better understanding of these inflammatory states can guide the design of therapeutics for restoring ocular surface health .
Employment
Employment history is unavailable.
Education
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Kwame Nkrumah University of Science and Technology, Kumasi. Doctor of Optometry2009 - Present
Projects & Funding
Projects & funding information is unavailable.
Publications (10)
- Meibomian Gland Dysfunction in Ocular Graft vs. Host Disease: A Need for Pre-Clinical Models and Deeper Insights Save
- Obese Mice with Dyslipidemia Exhibit Meibomian Gland Hypertrophy and Alterations in Meibum Composition and Aqueous Tear Production Save
- <p>Clinical Dry Eye and Meibomian Gland Features Among Dry Eye Patients in Rural and Urban Ghana</p> Save
- Dyslipidemia and Meibomian Gland Dysfunction: Utility of Lipidomics and Experimental Prospects with a Diet-Induced Obesity Mouse Model Save
- Assessment of meibomian glands using a custom–made meibographer in dry eye patients in Ghana Save
- Epidemiology of dry eye disease in Africa: The sparse information, gaps and opportunities. Save
- Assessment of corneal astigmatism following frown and straight incision forms in sutureless manual small incision cataract surgery Save
- Postoperative Corneal and Surgically Induced Astigmatism following Superior Approach Manual Small Incision Cataract Surgery in Patients with Preoperative Against-the-Rule Astigmatism Save
- Prevalence of overweight and obesity among students in the Kumasi metropolis Save
- Eye Diseases among Women Engaged in Local Extraction of Palm Kernel Oil in the Kumasi Metropolis Save