Yogavel Manickam

Employment

• International Centre For Genetic Engineering and Biotechnology New Delhi Postdoctoral Research Scientist
  2015 - Present
• International Centre For Genetic Engineering and Biotechnology New Delhi Postdoctoral Research Scientist
  2009 - 2014
• International Centre For Genetic Engineering and Biotechnology New Delhi Posdoctoral Fellow
  2006 - 2009

Education

• University of Madras Ph.D
  2000 - 2006
• Institute of Advanced Study in Education, Saidapet, Chennai - 600 015. B.Ed
  1999 - 2000
• University of Madras M.Sc
  1996 - 1999
• University of Madras B.Sc
  1993 - 1996

Projects & Funding

Projects & funding information is unavailable.

Publications (77)

• Chemical Targeting of Prolyl-tRNA Synthetase Stalls Ovarian Development and Kills Malaria Vectors
  The Journal of Infectious Diseases 2025 DOI: 10.1093/infdis/jiaf095
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• Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.
  PLoS pathogens 2023 DOI: 10.1371/journal.ppat.1011124
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• Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum
  Molecular and Biochemical Parasitology 2023 DOI: 10.1016/j.molbiopara.2022.111530
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• A single amino acid substitution alters activity and specificity in Plasmodium falciparum aspartyl & asparaginyl-tRNA synthetases.
  Molecular and biochemical parasitology 2022 DOI: 10.1016/j.molbiopara.2022.111488
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• Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development.
  PLoS pathogens 2022 DOI: 10.1371/journal.ppat.1010363
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• Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development.
  Structure (London, England : 1993) 2022 DOI: 10.1016/j.str.2022.03.017
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• Structural analyses of the malaria parasite aminoacyl-tRNA synthetases provide new avenues for antimalarial drug discovery.
  Protein science : a publication of the Protein Society 2021 DOI: 10.1002/pro.4148
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• Inhibition of Plasmodium falciparum Lysyl-tRNA Synthetase via a Piperidine-Ring Scaffold Inspired Cladosporin Analogues.
  Chembiochem : a European journal of chemical biology 2021 DOI: 10.1002/cbic.202100212
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• Design, Synthesis, and Structural Analysis of Cladosporin-Based Inhibitors of Malaria Parasites.
  ACS infectious diseases 2021 DOI: 10.1021/acsinfecdis.1c00092
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• Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines.
  Nature communications 2021 DOI: 10.1038/s41467-020-20478-5
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