Tom Tobias Fischer

Employment

• Hopp Children's Cancer Center Heidelberg

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (12)

• A single-cell atlas of cancer-educated ecotypes across high-risk pediatric sarcomas
  2026 DOI: 10.21203/rs.3.rs-10374394/v1
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• M-PACT leverages cell-free DNA methylomes to achieve robust classification of pediatric brain tumors
  Kyle S Smith, Tom T. Fischer, Katie Han +29 more
  Nature Cancer 2026 DOI: 10.1038/s43018-026-01115-4
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• Ultra-low-input cell-free DNA sequencing for tumor detection and characterization in a real-world pediatric brain tumor cohort
  Acta Neuropathologica Communications 2025 DOI: 10.1186/s40478-025-02024-w
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• Cerebrospinal fluid liquid biopsy guides differential diagnosis of relapsed medulloblastoma versus secondary glioma: A case report of a pediatric patient enrolled on a PDGFRA inhibitor trial
  Neuro-Oncology Advances 2025 DOI: 10.1093/noajnl/vdaf110
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• Boosting ER-mitochondria calcium transfer to treat Wolfram syndrome
  Cell Calcium 2022 DOI: 10.1016/j.ceca.2022.102572
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• Cytoskeletal dynamics regulates stromal invasion behavior of distinct liver cancer subtypes
  Communications Biology 2022 DOI: 10.1038/s42003-022-03121-5
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• Pharmacological rescue of cognitive function in a mouse model of chemobrain
  Molecular Neurodegeneration 2021 DOI: 10.1186/s13024-021-00463-2
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• Neuronal calcium sensor 1 (NCS1) dependent modulation of neuronal morphology and development
  The FASEB Journal 2021 DOI: 10.1096/fj.202100731R
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• Wolfram syndrome: a monogenic model for diabetes mellitus and neurodegeneration
  Current Opinion in Physiology 2020 DOI: 10.1016/j.cophys.2020.07.009
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• Calpain inhibitor and ibudilast rescue β cell functions in a cellular model of Wolfram syndrome
  Proceedings of the National Academy of Sciences 2020 DOI: 10.1073/pnas.2007136117
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• Neuronal Calcium Sensor 1 is up‐regulated in response to stress to promote cell survival and motility in cancer cells
  Molecular Oncology 2020 DOI: 10.1002/1878-0261.12678
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• Polycystin 2 is increased in disease to protect against stress-induced cell death
  Scientific Reports 2020 DOI: 10.1038/s41598-019-57286-x
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