Sagar Gupta

Employment

• Children's Hospital of Philadelphia Undergraduate Researcher
  2020 - 2024

Education

• University of Pennsylvania MD/PhD (Biochemistry, Biophysics, Chemical Biology)
  2024 - Present
• University of Pennsylvania Medical Student
  2024 - Present
• University of Pennsylvania MS – Chemistry
  2022 - 2024
• University of Pennsylvania BA – Biochemistry, Biology, Biophysics
  2020 - 2024

Projects & Funding

Projects & funding information is unavailable.

Publications (9)

• A structure-guided approach to predict MHC-I restriction of T cell receptors for public antigens
  Structure 2025 DOI: 10.1016/j.str.2025.06.011
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• Targeting peptide antigens using a multiallelic MHC I-binding system
  Nature Biotechnology 2024 DOI: 10.1038/s41587-024-02505-8
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• A structure-guided approach to predict MHC-I restriction of T cell receptors for public antigens
  2024 DOI: 10.1101/2024.06.04.597418
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• Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion
  Science Immunology 2023 DOI: 10.1126/sciimmunol.adj5792
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• HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes
  Nature Communications 2023 DOI: 10.1038/s41467-023-42163-z
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• Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes
  Proceedings of the National Academy of Sciences 2023 DOI: 10.1073/pnas.2304055120
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• Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion
  2023 DOI: 10.1101/2023.05.24.542108
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• HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes
  2023 DOI: 10.1101/2023.03.20.533510
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• Role of Alternative Elicitor Transporters in the Onset of Plant Host Colonization by Streptomyces scabiei 87-22
  Biology 2023 DOI: 10.3390/biology12020234
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