Hye Sun Kuehn

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Publications (7)

• CD8+ T cell loss induces autoinflammation in inborn errors of cell death
  Nature Communications 2026 DOI: 10.1038/s41467-026-70317-2
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• Systematic functional validation of IKAROS variants from patients and laboratory-generated mutations
  Blood Advances 2026 DOI: 10.1182/bloodadvances.2025017243
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• IKAROS regulates human T cell phenotype at a thymic and postthymic level
  JCI Insight 2025 DOI: 10.1172/jci.insight.197359
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• Disease-associated AIOLOS variants lead to immune deficiency/dysregulation by haploinsufficiency and redefine AIOLOS functional domains
  Journal of Clinical Investigation 2024 DOI: 10.1172/JCI172573
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• Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling
  Nature Communications 2023 DOI: 10.1038/s41467-023-39272-0
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• A Heterozygous Gain-of-Function Variant in IKBKB Associated with Autoimmunity and Autoinflammation
  Keith A. Sacco, Hye Sun Kuehn, Tomoki Kawai

  +10 more

  • Nouf Alsaati
  • Lauren Leigh Smith
  • Blachy J. Dávila Saldaña
  • Vanessa L. Bundy
  • Douglas Byron Kuhns
  • +5 more
  Journal of Clinical Immunology 2023 DOI: 10.1007/s10875-022-01395-2
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• T and B cell abnormalities, pneumocystis pneumonia, and chronic lymphocytic leukemia associated with an AIOLOS defect in patients
  Journal of Experimental Medicine 2021 DOI: 10.1084/jem.20211118
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