Peerzada Shariq Shaheen Khaki
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Protein Structure and Dynamics · Alzheimer's disease research and treatments · Protease and Inhibitor Mechanisms
0000-0002-2237-8800
About
Dr. Peerzada Shariq Shaheen Khaki is a biochemist and educator whose research explores protein misfolding disorders, functional amyloids, and protease biology. He is currently a Postdoctoral Fellow at the School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, where he applies cryogenic electron microscopy (Cryo‑EM) to study the molecular architecture of amyloids. His work has appeared in Nature Structural & Molecular Biology, PNAS, and Cell (under revision).
He earned his Ph.D. in Biochemistry from Aligarh Muslim University, India, following earlier degrees in Biochemistry and Medical Laboratory Technology. He has taught biochemistry at medical colleges in India, developing a pedagogy that integrates research with student engagement.
Dr. Khaki’s publications include studies on amyloid‑β filament folds in postmortem Alzheimer’s disease cases with Flemish mutation and functional amyloids in memory regulation, alongside broader contributions to protease biochemistry and clinical biochemistry. His peer‑reviewed research adds to the scientific literature on protein misfolding, functional amyloids, and related biomedical fields.
Beyond research, he is committed to mentoring future scientists and advancing biomedical innovation through education and collaboration. He has presented at international symposia, delivered invited talks, and participated in professional development workshops in Cryo‑EM, computational biology, and medical education.
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Publications (16)
- Distinct amyloid-β filament fold in individuals with APP Flemish mutation Save
- A J-domain protein enhances memory by promoting physiological amyloid formation in Drosophila Save
- Bladder cancer: PI3K/Akt/mTOR signaling dysregulation, potential proteomic techniques, therapeutic strategies, and future perspectives Save
- Structural Evolution of a Functional Amyloid Underlies Age-Related Memory Impairment in Drosophila Save
- Anticancer Activity of Natural Compounds Save
- Urea induced unfolding of rai seed cystatin: Influence of glycerol as a chemical chaperone Save
- Protein aggregation as a consequence of non-enzymatic glycation: Therapeutic intervention using aspartic acid and arginine. Save
- An Update on the Association of Protein Kinases with Cardiovascular Diseases. Save
- Alzheimer’s: A progressive brain disease: Causes, symptoms, and prevention Save
- Purification and characterization of a cystatin like thiol protease inhibitor from Brassica nigra. Save
- Glycation induced conformational alterations in caprine brain cystatin (CBC) leads to aggregation via passage through a partially folded state. Save
- Binding of λ-carrageenan (a food additive) to almond cystatin: An insight involving spectroscopic and thermodynamic approach. Save
- Isolation and purification of phytocystatin from almond: Biochemical, biophysical, and immunological characterization Save
- Interaction of almond cystatin with pesticides: Structural and functional analysis. Save
- Structural and functional studies on a variant of cystatin purified from brain of Capra hircus. Save
- Employing in vitro analysis to test the potency of methylglyoxal in inducing the formation of amyloid-like aggregates of caprine brain cystatin. Save