Chandi C Mandal
Also known as: Chandi C Mandal
Central University of Rajasthan, Sharda University
About
Prof. Chandi C. Mandal: Professor, Department of Biochemistry, Central University of Rajasthan, India [2013 to present]; Postdoctoral training from University of Texas Health Science Center at San Antonio, Texas, USA [2006-2012]; Ph.D. from Indian Institute of Technology at Kharagpur, India [2000-2005]; M.Sc. (Biochemistry) from Calcutta University, India.
Prof. Chandi C. Mandal's research aims at understanding molecular mechanisms of dysregulated gene expressions and cellular signaling networks associated with debilitating cancer diseases, by carrying out cell-based experiments, cancer tissue and database analysis. Exploring the impact of various metabolic disorders including diabetes, obesity and hypercholesterolemia, and extrinsic risk factor (cold temperature) on the peculiar trans-differentiation property of epithelial breast cancer cells into osteoblast- and adipocyte-like cells is a major focus. Non-toxic drug candidates are preferred to cease dysregulated signaling pathways via hindering the gene targets. Research of this laboratory also seeks to examine if cholesterol-lowering statins, omega-3 fatty acids and anti-diabetic metformin can be combined with other anti-cancer drugs to show better.
Dr. Mandal's academic endeavour is not only reflected in the publications of his research work, but he is also recipient of Investigator Award from ASBMR, USA and fellowship Award from CPRIT, USA. His research work has also been highlighted multiple times in Newspaper and reported in Television channels. He is a member of several professional societies such as IACR, BRSI, ISCA. Prof. Mandal is fellow of Royal Society of Biology (FRSB) UK, Executive Member of Indian Association of Cancer Research. He is editorial board member of various journals such as associate editor of “Frontiers in Endocrinology-bone section” and “BMC Cancer”, and academic editor of “PLOS ONE”, and editorial member of "Scientific Reports [npg]", "Journal of Biochemical and Molecular Toxicology”, "Oncology Letters", “Current Drug Targets" and "Indian Journal of Medical Research". He has enlisted in the TOP 2% scientists in the world made by Stanford University in 2021 and 2023-2025, published in Plos Biology.
He has published 70 plus research papers in international journals with h-index 32 & i10 index 52 and published also 50 plus abstracts in various reputed conferences.
Area of Interest: Cellular Signaling associated with Cancer and Bone Biology.
Research Keywords:
Cancer Cell biology, Cellular signaling, Bone metastasis, Bone remodeling, Cancer calcification, Osteoblast, Osteoclast, Apoptosis, Epithelial to mesenchymal transition, metabolic disease associated cancer risk, Tumor microenvironment, Bone Morphogenetic Protein Signaling, Epigenetics, Environment temperature , Trans-differentiation of cancer cells, Oncogene discovery
Employment
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Central University of Rajasthan Professor2019 - Present
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Central University of Rajasthan Associate Professor2016 - 2019
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Central University of Rajasthan Assistant Professor2013 - 2016
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Sharda University Assistant Professor2012 - 2013
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (70)
- ZNF468 Exhibits Oncogenic Activity by Regulating Unexplored ZNF707 in Breast Cancer Save
- Unexplored gene PHKA1 interplays between glucose metabolism and breast cancer Save
- Multifaceted In Silico Screening Strategies Identifies Potent Inhibitors Facilitating Inhibition of <scp>ZNF726</scp> Activity in Breast Cancer Save
- Lipid metabolism dysregulation for bone metastasis and its prevention Save
- Lipid metabolism associated PLPP4 gene drives oncogenic and adipogenic potential in breast cancer cells Save
- Editorial: Bone cell differentiation in health and disease, volume II Save
- Targeting TRIM26: Unveiling an Oncogene and Identification of Plant Metabolites as a Potential Therapeutics for Breast Cancer Save
- Metformin prevents osteoblast-like potential and calcification in lung cancer A549 cells. Save
- A Perspective on Bone Morphogenetic Proteins: Dilemma behind Cancer- related Responses. Save
- Dysregulated cholesterol regulatory genes as a diagnostic biomarker for cancer. Save